Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014: a population-based study
Background - The aim was to compare population-based survival for exocrine pancreatic cancer in England in the 23 regions covered by specialist centres. The centres were initiated in 2001, covering populations of 2-4 million. - Methods - We examined incidence for adults diagnosed with a pancreatic e...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 January 2020
|
| In: |
Pancreatology
Year: 2020, Jahrgang: 20, Heft: 3, Pages: 454-461 |
| ISSN: | 1424-3911 |
| DOI: | 10.1016/j.pan.2020.01.012 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pan.2020.01.012 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S1424390320300302 
|
| Verfasserangaben: | Aimilia Exarchakou, Georgia Papacleovoulou, Brian Rous, Winnie Magadi, Bernard Rachet, John P. Neoptolemos, Michel P. Coleman |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1700294245 | ||
| 003 | DE-627 | ||
| 005 | 20220818115512.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200610s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.pan.2020.01.012 |2 doi | |
| 035 | |a (DE-627)1700294245 | ||
| 035 | |a (DE-599)KXP1700294245 | ||
| 035 | |a (OCoLC)1341333023 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Exarchakou, Aimilia |e VerfasserIn |0 (DE-588)1211674282 |0 (DE-627)1700294067 |4 aut | |
| 245 | 1 | 0 | |a Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014 |b a population-based study |c Aimilia Exarchakou, Georgia Papacleovoulou, Brian Rous, Winnie Magadi, Bernard Rachet, John P. Neoptolemos, Michel P. Coleman |
| 264 | 1 | |c 22 January 2020 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.06.2020 | ||
| 520 | |a Background - The aim was to compare population-based survival for exocrine pancreatic cancer in England in the 23 regions covered by specialist centres. The centres were initiated in 2001, covering populations of 2-4 million. - Methods - We examined incidence for adults diagnosed with a pancreatic exocrine cancer during 1995-2014 and age-standardised net survival up to five years after diagnosis for patients diagnosed during 2000-2013. We examined variation in regional resection rates and survival for patients diagnosed during 2010-2013. The data were extracted from the National Cancer Registration and Analysis Service. - Results - Age-standardised annual incidence rates of exocrine pancreatic cancer increased from 17.1 per 100,000 during 1995-1999 to 18.7 during 2010-2014. Age-standardised one-year and five-year net survival increased from 17.9% and 3.6%, respectively, for 2000-2009, to 21.6% and 4.2% during 2010-2013. There were 2086 (8.9%) resections among 23,415 patients diagnosed with an exocrine tumour in 2010-2013. The proportion ranged from 5.1% to 19.6% between centres. Among resected patients, survival was 73.0% at one year and 20.2% at five years. Of the total 2118 resected patients, 18 (0.9%) were at stage 1; 34 (1.6%) at stage 2; 791 (37.3%) at stage 3 and 140 (6.6%) at stage 4, although 53.6% of stage information was missing. Five-year survival was 2.1% for those who were not resected. The number of resections performed in each centre was not correlated with one-year survival. - Conclusions - Despite improvements in the management of pancreatic cancer in England with the introduction of specialist centres, resection rates remain relatively low, and survival remains lower than in comparably wealthy countries. | ||
| 650 | 4 | |a Adjuvant therapy | |
| 650 | 4 | |a Chemotherapy | |
| 650 | 4 | |a Pancreatectomy | |
| 650 | 4 | |a Survival | |
| 650 | 4 | |a Tumour staging | |
| 650 | 4 | |a Volume | |
| 700 | 1 | |a Papacleovoulou, Georgia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rous, Brian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Magadi, Winnie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rachet, Bernard |e VerfasserIn |4 aut | |
| 700 | 1 | |a Neoptolemos, John P. |e VerfasserIn |0 (DE-588)172283302 |0 (DE-627)697192954 |0 (DE-576)133150879 |4 aut | |
| 700 | 1 | |a Coleman, Michel P. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Pancreatology |d Amsterdam : Elsevier, 2001 |g 20(2020), 3, Seite 454-461 |h Online-Ressource |w (DE-627)32764432X |w (DE-600)2043694-4 |w (DE-576)110513657 |x 1424-3911 |7 nnas |a Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014 a population-based study |
| 773 | 1 | 8 | |g volume:20 |g year:2020 |g number:3 |g pages:454-461 |g extent:8 |a Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014 a population-based study |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.pan.2020.01.012 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S1424390320300302 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200610 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 172283302 |a Neoptolemos, John P. |m 172283302:Neoptolemos, John P. |d 910000 |d 910200 |e 910000PN172283302 |e 910200PN172283302 |k 0/910000/ |k 1/910000/910200/ |p 6 | ||
| 999 | |a KXP-PPN1700294245 |e 3684987549 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedDisp":"22 January 2020","dateIssuedKey":"2020"}],"physDesc":[{"extent":"8 S."}],"person":[{"family":"Exarchakou","roleDisplay":"VerfasserIn","given":"Aimilia","role":"aut","display":"Exarchakou, Aimilia"},{"display":"Papacleovoulou, Georgia","role":"aut","given":"Georgia","roleDisplay":"VerfasserIn","family":"Papacleovoulou"},{"role":"aut","display":"Rous, Brian","given":"Brian","family":"Rous","roleDisplay":"VerfasserIn"},{"display":"Magadi, Winnie","role":"aut","given":"Winnie","family":"Magadi","roleDisplay":"VerfasserIn"},{"given":"Bernard","role":"aut","display":"Rachet, Bernard","roleDisplay":"VerfasserIn","family":"Rachet"},{"given":"John P.","display":"Neoptolemos, John P.","role":"aut","family":"Neoptolemos","roleDisplay":"VerfasserIn"},{"display":"Coleman, Michel P.","role":"aut","given":"Michel P.","roleDisplay":"VerfasserIn","family":"Coleman"}],"name":{"displayForm":["Aimilia Exarchakou, Georgia Papacleovoulou, Brian Rous, Winnie Magadi, Bernard Rachet, John P. Neoptolemos, Michel P. Coleman"]},"relHost":[{"recId":"32764432X","pubHistory":["1.2001 -"],"disp":"Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014 a population-based studyPancreatology","note":["Gesehen am 09.01.2019"],"id":{"issn":["1424-3911"],"eki":["32764432X"],"zdb":["2043694-4"]},"title":[{"title":"Pancreatology","title_sort":"Pancreatology","subtitle":"official journal of the International Association of Pancreatology (IAP) and the European Pancreatic Club (EPC)"}],"language":["eng"],"origin":[{"publisher":"Elsevier ; Karger","dateIssuedDisp":"2001-","dateIssuedKey":"2001","publisherPlace":"Amsterdam ; Basel"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"part":{"pages":"454-461","year":"2020","extent":"8","issue":"3","volume":"20","text":"20(2020), 3, Seite 454-461"},"physDesc":[{"extent":"Online-Ressource"}]}],"title":[{"subtitle":"a population-based study","title":"Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014","title_sort":"Pancreatic cancer incidence and survival and the role of specialist centres in resection rates in England, 2000 to 2014"}],"id":{"eki":["1700294245"],"doi":["10.1016/j.pan.2020.01.012"]},"recId":"1700294245","note":["Gesehen am 10.06.2020"]} | ||
| SRT | |a EXARCHAKOUPANCREATIC2220 | ||