The effect of disease risk probability and disease type on interest in clinic-based versus direct-to-consumer genetic testing services
The effect of disease-specific cognitions on interest in clinic-based and direct-to-consumer (DTC) genetic testing was assessed. Participants (N = 309) responded to an online hypothetical scenario and received genetic testing-related messages that varied by risk probability (25, 50, 75 %) and diseas...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 27, 2015
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| In: |
Journal of behavioral medicine
Year: 2015, Volume: 38, Issue: 5, Pages: 706-714 |
| ISSN: | 1573-3521 |
| DOI: | 10.1007/s10865-015-9630-9 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10865-015-9630-9
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| Author Notes: | Kerry Sherman, Laura-Kate Shaw, Katrina Champion, Fernanda Caldeira, Margaret McCaskill |
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| 520 | |a The effect of disease-specific cognitions on interest in clinic-based and direct-to-consumer (DTC) genetic testing was assessed. Participants (N = 309) responded to an online hypothetical scenario and received genetic testing-related messages that varied by risk probability (25, 50, 75 %) and disease type (Alzheimer’s disease vs. Type 2 Diabetes). Post-manipulation interest increased for both testing types, but was greater for clinic-based testing. Interest was greater for Type 2 Diabetes than for Alzheimer’s disease, the latter perceived as more severe and likely, and less treatable and preventable. For DTC testing only, participants allocated to the high risk condition (75 %) had greater testing interest than those in the low (25 %) category. DTC testing is perceived as a viable, but less preferred, option compared with clinic-based testing. Particularly when considering DTC genetic testing, there is a need to emphasize subjective disease-related perceptions, including risk probability. | ||
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