Allelic ratio of KRAS mutations in pancreatic cancer

KRAS is not simply mutated or wild type in pancreatic ductal adenocarcinoma (PDAC); actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however, the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of mutated KRAS.

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Hauptverfasser: Lennerz, Jochen K. (VerfasserIn) , Stenzinger, Albrecht (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 16 March 2015
In: The oncologist
Year: 2015, Jahrgang: 20, Heft: 4, Pages: e8-e9
ISSN:1549-490X
DOI:10.1634/theoncologist.2014-0408
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1634/theoncologist.2014-0408
Verlag, lizenzpflichtig, Volltext: https://theoncologist.onlinelibrary.wiley.com/doi/abs/10.1634/theoncologist.2014-0408
Volltext
Verfasserangaben:Jochen K. Lennerz, Albrecht Stenzinger

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