EZH2 mutations and impact on clinical outcome: an analysis in 1,604 patients with newly diagnosed acute myeloid leukemia

The enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and functional core subunit of the polycomb repressive complex 2 (PRC2), which is a key epigenetic regulator involved in embryonic development and transcriptional repression of genes by catalyzing the methylation of histone H3 at

Bibliographic Details

Main Authors:	Stasik, Sebastian (Author) , Krämer, Alwin (Author) , Müller-Tidow, Carsten (Author)
Format:	Article (Journal) Editorial
Language:	English
Published:	2020
In:	Haematologica Year: 2020, Volume: 105, Issue: 5, Pages: e228-e231
ISSN:	1592-8721
DOI:	10.3324/haematol.2019.222323
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3324/haematol.2019.222323 Verlag, lizenzpflichtig, Volltext: http://www.haematologica.org/content/105/5/e228
Author Notes:	Sebastian Stasik, Jan M. Middeke, Michael Kramer, Christoph Röllig, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Volker Kunzmann, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan Krause, Regina Herbst, Mathias Hänel, Norbert Frickhofen, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Zdenek Rácil, Uwe Platzbecker, Wolfgang E. Berdel, Jiri Mayer, Hubert Serve, Carsten Müller-Tidow, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Christian Thiede