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Short- and long-term effects of brain death on post-transplant graft function in a rodent model

Heart transplantation has become the most effective treatment for end-stage heart failure. Donors after brain death (BD) are currently the only reliable source for cardiac transplants. However, haemodynamic instability and cardiac dysfunction have been demonstrated in brain-dead donors and this coul...

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Hauptverfasser: Li, Shiliang (VerfasserIn) , Korkmaz-İçöz, Sevil (VerfasserIn) , Loganathan, Sivakkanan (VerfasserIn) , Radovits, Tamás (VerfasserIn) , Hegedűs, Péter (VerfasserIn) , Karck, Matthias (VerfasserIn) , Szabó, Gábor (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2015
In: Interactive cardiovascular and thoracic surgery
Year: 2014, Jahrgang: 20, Heft: 3, Pages: 379-386
ISSN:1569-9285
DOI:10.1093/icvts/ivu403
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/icvts/ivu403
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/icvts/article/20/3/379/682313
Volltext
Verfasserangaben:Shiliang Li, Sevil Korkmaz, Sivakkanan Loganathan, Tamás Radovits, Peter Hegedűs, Matthias Karck and Gábor Szabó
Beschreibung
Zusammenfassung:Heart transplantation has become the most effective treatment for end-stage heart failure. Donors after brain death (BD) are currently the only reliable source for cardiac transplants. However, haemodynamic instability and cardiac dysfunction have been demonstrated in brain-dead donors and this could therefore also affect post-transplant graft function. We studied the effects of BD on cardiac function and its short-term (1 h) or long-term (5 h) impacts on graft function.
Beschreibung:Advance access publication 11 December 2014
Gesehen am 22.06.2020
Beschreibung:Online Resource
ISSN:1569-9285
DOI:10.1093/icvts/ivu403

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