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MiRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6

MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo.

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Bibliographische Detailangaben
Hauptverfasser: Oglesby, Irene K. (VerfasserIn) , Agrawal, Raman (VerfasserIn) , Mall, Marcus A. (VerfasserIn) , McElvaney, Noel G. (VerfasserIn) , Greene, Catherine M. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 07 January 2015
In: Molecular and Cellular Pediatrics
Year: 2015, Jahrgang: 2, Heft: 1
ISSN:2194-7791
DOI:10.1186/s40348-014-0012-0
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s40348-014-0012-0
Volltext
Verfasserangaben:Irene K. Oglesby, Raman Agrawal, Marcus A. Mall, Noel G. McElvane and Catherine M. Greene
Beschreibung
Zusammenfassung:MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo.
Beschreibung:Gesehen am 22.06.2020
Beschreibung:Online Resource
ISSN:2194-7791
DOI:10.1186/s40348-014-0012-0

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