The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva
The oral cavity with the teeth and the surrounding gingival epithelium, the periodontium, the salivary glands and other structures are open to the oral environment and thus exposed to multiple microbiological and pathogenic influences. To prevent permanent inflammatory processes such as gingivitis o...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2015
|
| In: |
Annals of anatomy
Year: 2015, Jahrgang: 199, Pages: 92-97 |
| ISSN: | 1618-0402 |
| DOI: | 10.1016/j.aanat.2014.05.040 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.aanat.2014.05.040 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0940960214001289 
|
| Verfasserangaben: | Martin Schicht, Christina Stengl, Sadettin Sel, Friedhelm Heinemann, Werner Götz, Anselm Petschelt, Matthias Pelka, Michael Scholz, Felix Rausch, Friedrich Paulsen, Lars Bräuer |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1702026124 | ||
| 003 | DE-627 | ||
| 005 | 20250804142942.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200624s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.aanat.2014.05.040 |2 doi | |
| 035 | |a (DE-627)1702026124 | ||
| 035 | |a (DE-599)KXP1702026124 | ||
| 035 | |a (OCoLC)1341341587 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Schicht, Martin |e VerfasserIn |0 (DE-588)14381964X |0 (DE-627)704611384 |0 (DE-576)339061421 |4 aut | |
| 245 | 1 | 4 | |a The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva |c Martin Schicht, Christina Stengl, Sadettin Sel, Friedhelm Heinemann, Werner Götz, Anselm Petschelt, Matthias Pelka, Michael Scholz, Felix Rausch, Friedrich Paulsen, Lars Bräuer |
| 264 | 1 | |c 2015 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Available online 23 June 2014 | ||
| 500 | |a Gesehen am 24.06.2020 | ||
| 520 | |a The oral cavity with the teeth and the surrounding gingival epithelium, the periodontium, the salivary glands and other structures are open to the oral environment and thus exposed to multiple microbiological and pathogenic influences. To prevent permanent inflammatory processes such as gingivitis or periodontitis an efficient defense system is essential to ensure healthy and physiological function of the oral cavity and other interacting organic systems. Surfactant proteins (SPs), originally found in pulmonary tissue are important factors of the immune system and beyond this, support the stability and rheology of gas or fluid interfaces. This study aimed to analyze the distribution of surfactant proteins by means of Western blot and immunohistochemistry in salivary glands as well as in healthy and pathological saliva. The different expression patterns of SP-A, -B, -C and -D in healthy and pathological (periodontitis) saliva were determined using ELISA quantification. One further objective of the study was the first detection of two recent discovered proteins belonging to the surfactant protein family within human salivary glands and saliva. The results of the study reveal differences in protein expression of SP-A, -B, -C and -D within healthy and pathologic saliva. The concentration of the surfactant proteins SP-A, SP-C and SP-D is increased in saliva of people suffering from periodontal diseases, whereas by contrast, SP-B shows an opposite expression pattern. Furthermore, the results evidence the presence of SP-G and SP-H within saliva and salivary glands for the first time. | ||
| 650 | 4 | |a Gingivitis | |
| 650 | 4 | |a Periodontitis | |
| 650 | 4 | |a Saliva | |
| 650 | 4 | |a Surfactant proteins | |
| 700 | 1 | |a Stengl, Christina |d 1984- |e VerfasserIn |0 (DE-588)1060417235 |0 (DE-627)799766194 |0 (DE-576)416504841 |4 aut | |
| 700 | 1 | |a Sel, Saadettin |d 1968- |e VerfasserIn |0 (DE-588)122466926 |0 (DE-627)081961472 |0 (DE-576)293284474 |4 aut | |
| 700 | 1 | |a Heinemann, Friedhelm |e VerfasserIn |4 aut | |
| 700 | 1 | |a Götz, Werner |e VerfasserIn |4 aut | |
| 700 | 1 | |a Petschelt, Anselm |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pelka, Matthias |e VerfasserIn |4 aut | |
| 700 | 1 | |a Scholz, Michael |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rausch, Felix |e VerfasserIn |4 aut | |
| 700 | 1 | |a Paulsen, Friedrich |d 1965- |e VerfasserIn |0 (DE-588)124866697 |0 (DE-627)367231794 |0 (DE-576)294542205 |4 aut | |
| 700 | 1 | |a Bräuer, Lars |d 1977- |e VerfasserIn |0 (DE-588)132370697 |0 (DE-627)521911907 |0 (DE-576)299103447 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Annals of anatomy |d Jena : Elsevier, 1992 |g 199(2015), Seite 92-97 |h Online-Ressource |w (DE-627)483300594 |w (DE-600)2182566-X |w (DE-576)252074742 |x 1618-0402 |7 nnas |a The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva |
| 773 | 1 | 8 | |g volume:199 |g year:2015 |g pages:92-97 |g extent:6 |a The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.aanat.2014.05.040 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0940960214001289 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200624 | ||
| 993 | |a Article | ||
| 994 | |a 2015 | ||
| 998 | |g 122466926 |a Sel, Saadettin |m 122466926:Sel, Saadettin |d 910000 |d 910900 |e 910000PS122466926 |e 910900PS122466926 |k 0/910000/ |k 1/910000/910900/ |p 3 | ||
| 999 | |a KXP-PPN1702026124 |e 3690747392 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"eki":["1702026124"],"doi":["10.1016/j.aanat.2014.05.040"]},"origin":[{"dateIssuedKey":"2015","dateIssuedDisp":"2015"}],"name":{"displayForm":["Martin Schicht, Christina Stengl, Sadettin Sel, Friedhelm Heinemann, Werner Götz, Anselm Petschelt, Matthias Pelka, Michael Scholz, Felix Rausch, Friedrich Paulsen, Lars Bräuer"]},"relHost":[{"recId":"483300594","language":["eng"],"note":["Gesehen am 09.11.2020"],"disp":"The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingivaAnnals of anatomy","type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"year":"2015","pages":"92-97","volume":"199","text":"199(2015), Seite 92-97","extent":"6"},"pubHistory":["174.1992 -"],"titleTranslated":[{"translated":"Anatomischer Anzeiger"}],"title":[{"title_sort":"Annals of anatomy","title":"Annals of anatomy","subtitle":"official organ of the Anatomische Gesellschaft = Anatomischer Anzeiger"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["483300594"],"zdb":["2182566-X"],"issn":["1618-0402"]},"origin":[{"publisherPlace":"Jena","dateIssuedKey":"1992","publisher":"Elsevier","dateIssuedDisp":"1992-"}]}],"physDesc":[{"extent":"6 S."}],"title":[{"title_sort":"distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva","title":"The distribution of human surfactant proteins within the oral cavity and their role during infectious diseases of the gingiva"}],"person":[{"given":"Martin","family":"Schicht","role":"aut","roleDisplay":"VerfasserIn","display":"Schicht, Martin"},{"given":"Christina","family":"Stengl","role":"aut","roleDisplay":"VerfasserIn","display":"Stengl, Christina"},{"display":"Sel, Saadettin","roleDisplay":"VerfasserIn","role":"aut","family":"Sel","given":"Saadettin"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Heinemann, Friedhelm","given":"Friedhelm","family":"Heinemann"},{"given":"Werner","family":"Götz","role":"aut","display":"Götz, Werner","roleDisplay":"VerfasserIn"},{"display":"Petschelt, Anselm","roleDisplay":"VerfasserIn","role":"aut","family":"Petschelt","given":"Anselm"},{"role":"aut","display":"Pelka, Matthias","roleDisplay":"VerfasserIn","given":"Matthias","family":"Pelka"},{"family":"Scholz","given":"Michael","display":"Scholz, Michael","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Felix","family":"Rausch","role":"aut","display":"Rausch, Felix","roleDisplay":"VerfasserIn"},{"display":"Paulsen, Friedrich","roleDisplay":"VerfasserIn","role":"aut","family":"Paulsen","given":"Friedrich"},{"role":"aut","display":"Bräuer, Lars","roleDisplay":"VerfasserIn","given":"Lars","family":"Bräuer"}],"language":["eng"],"recId":"1702026124","note":["Available online 23 June 2014","Gesehen am 24.06.2020"],"type":{"media":"Online-Ressource","bibl":"article-journal"}} | ||
| SRT | |a SCHICHTMARDISTRIBUTI2015 | ||