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One, two or three?: Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is...

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Main Authors: Fricke, Franziska (Author) , Beaudouin, Joël (Author) , Eils, Roland (Author) , Heilemann, Mike (Author)
Format: Article (Journal)
Language:English
Published: 11 September 2015
In: Scientific reports
Year: 2015, Volume: 5, Pages: 1-8
ISSN:2045-2322
DOI:10.1038/srep14072
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/srep14072
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/srep14072
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Author Notes:Franziska Fricke, Joel Beaudouin, Roland Eils & Mike Heilemann

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