Characterization of ClpS2, an essential adaptor protein for the cyanobacterium Synechococcus elongatus
The adaptor protein ClpS associates to the Clp protease and promotes degradation of N-end rule substrates in eubacteria and in algal/plant chloroplasts. Cyanobacteria are unusual in having two distinct ClpS paralogs. Although ClpSl is typical of bacterial ClpS, ClpS2 differs in crucial ways. ClpS2 i...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 November 2
|
| In: |
FEBS letters
Year: 2015, Jahrgang: 589, Heft: 24, part B, Pages: 4039-4046 |
| ISSN: | 1873-3468 |
| DOI: | 10.1016/j.febslet.2015.11.026 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.febslet.2015.11.026 Verlag, lizenzpflichtig, Volltext: https://febs.onlinelibrary.wiley.com/doi/abs/10.1016/j.febslet.2015.11.026 
|
| Verfasserangaben: | Anders Tryggvesson, Frida M. Ståhlberg, Mats Töpel, Noriaki Tanabe, Axel Mogk, Adrian K. Clarke |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1703731107 | ||
| 003 | DE-627 | ||
| 005 | 20220818142221.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200706s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.febslet.2015.11.026 |2 doi | |
| 035 | |a (DE-627)1703731107 | ||
| 035 | |a (DE-599)KXP1703731107 | ||
| 035 | |a (OCoLC)1341344714 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Tryggvesson, Anders |e VerfasserIn |0 (DE-588)1166577112 |0 (DE-627)1030487499 |0 (DE-576)51080182X |4 aut | |
| 245 | 1 | 0 | |a Characterization of ClpS2, an essential adaptor protein for the cyanobacterium Synechococcus elongatus |c Anders Tryggvesson, Frida M. Ståhlberg, Mats Töpel, Noriaki Tanabe, Axel Mogk, Adrian K. Clarke |
| 264 | 1 | |c 24 November 2 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 06.07.2020 | ||
| 520 | |a The adaptor protein ClpS associates to the Clp protease and promotes degradation of N-end rule substrates in eubacteria and in algal/plant chloroplasts. Cyanobacteria are unusual in having two distinct ClpS paralogs. Although ClpSl is typical of bacterial ClpS, ClpS2 differs in crucial ways. ClpS2 in Synechococcus elongatus is a relatively low-abundant, soluble protein essential for phototrophic growth. Like ClpSl, ClpS2 binds to the ClpCP3/R protease to block α-casein degradation and promote that of N-end rule substrates in vitro. However, their substrate specificity differs, with ClpSl recognizing destabilizing Phe and Tyr residues at the substrate N-terminus whereas ClpS2 recognizes Leu. Overall, ClpS2 appears to have independently evolved in cyanobacteria to degrade a particular group of proteins, whose turnover is vital for cell viability. | ||
| 650 | 4 | |a ClpS adaptor | |
| 650 | 4 | |a N-end rule | |
| 650 | 4 | |a Proteolysis | |
| 650 | 4 | |a Synechococcus elongatus | |
| 700 | 1 | |a Ståhlberg, Frida M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Töpel, Mats |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tanabe, Noriaki |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mogk, Axel |e VerfasserIn |0 (DE-588)102799914X |0 (DE-627)73031166X |0 (DE-576)180449338 |4 aut | |
| 700 | 1 | |a Clarke, Adrian K. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |a Vereinigung der Europäischen Biochemischen Gesellschaften |t FEBS letters |d Chichester : Wiley, 1968 |g 589(2015), 24, part B, Seite 4039-4046 |h Online-Ressource |w (DE-627)253779669 |w (DE-600)1460391-3 |w (DE-576)07279383X |x 1873-3468 |7 nnas |
| 773 | 1 | 8 | |g volume:589 |g year:2015 |g number:24, part B |g pages:4039-4046 |g extent:8 |a Characterization of ClpS2, an essential adaptor protein for the cyanobacterium Synechococcus elongatus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.febslet.2015.11.026 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://febs.onlinelibrary.wiley.com/doi/abs/10.1016/j.febslet.2015.11.026 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200706 | ||
| 993 | |a Article | ||
| 994 | |a 2015 | ||
| 998 | |g 102799914X |a Mogk, Axel |m 102799914X:Mogk, Axel |d 700000 |d 706000 |e 700000PM102799914X |e 706000PM102799914X |k 0/700000/ |k 1/700000/706000/ |p 5 |y j | ||
| 999 | |a KXP-PPN1703731107 |e 369575897X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"recId":"1703731107","note":["Gesehen am 06.07.2020"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"person":[{"given":"Anders","family":"Tryggvesson","role":"aut","roleDisplay":"VerfasserIn","display":"Tryggvesson, Anders"},{"family":"Ståhlberg","given":"Frida M.","roleDisplay":"VerfasserIn","display":"Ståhlberg, Frida M.","role":"aut"},{"role":"aut","display":"Töpel, Mats","roleDisplay":"VerfasserIn","given":"Mats","family":"Töpel"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Tanabe, Noriaki","given":"Noriaki","family":"Tanabe"},{"given":"Axel","family":"Mogk","role":"aut","display":"Mogk, Axel","roleDisplay":"VerfasserIn"},{"given":"Adrian K.","family":"Clarke","role":"aut","roleDisplay":"VerfasserIn","display":"Clarke, Adrian K."}],"title":[{"title":"Characterization of ClpS2, an essential adaptor protein for the cyanobacterium Synechococcus elongatus","title_sort":"Characterization of ClpS2, an essential adaptor protein for the cyanobacterium Synechococcus elongatus"}],"relHost":[{"id":{"eki":["253779669"],"doi":["10.1002/(ISSN)1873-3468"],"zdb":["1460391-3"],"issn":["1873-3468"]},"origin":[{"publisherPlace":"Chichester ; Amsterdam ; Amsterdam [u.a.]","dateIssuedKey":"1968","publisher":"Wiley ; North-Holland Publ. Co. ; Elsevier","dateIssuedDisp":"1968-"}],"name":{"displayForm":["Federation of European Biochemical Societies. Ed. M. Avron [u.a.]"]},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"FEBS letters","subtitle":"for the rapid publication of short reports in biochemistry, biophysics, and molecular biology","title":"FEBS letters"}],"part":{"text":"589(2015), 24, part B, Seite 4039-4046","volume":"589","extent":"8","year":"2015","pages":"4039-4046","issue":"24, part B"},"pubHistory":["1.1968 -"],"language":["eng"],"corporate":[{"role":"aut","display":"Vereinigung der Europäischen Biochemischen Gesellschaften","roleDisplay":"VerfasserIn"}],"recId":"253779669","type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Vereinigung der Europäischen Biochemischen GesellschaftenFEBS letters","note":["Gesehen am 18.12.2019","Fortsetzung der Druck-Ausgabe"]}],"physDesc":[{"extent":"8 S."}],"name":{"displayForm":["Anders Tryggvesson, Frida M. Ståhlberg, Mats Töpel, Noriaki Tanabe, Axel Mogk, Adrian K. Clarke"]},"id":{"eki":["1703731107"],"doi":["10.1016/j.febslet.2015.11.026"]},"origin":[{"dateIssuedDisp":"24 November 2","dateIssuedKey":"2015"}]} | ||
| SRT | |a TRYGGVESSOCHARACTERI242 | ||