A coding-independent function of an alternative Ube3a transcript during neuronal development
This work shows a nocoding function of Ube3a1 RNA, an alternative transcript encoded by the Angelman syndrome gene Ube3a. Valluy et al. observe that Ube3a1 RNA competes with dendritic mRNAs for microRNAs, thereby regulating dendrite arborization and spine maturation of hippocampal neurons. These fin...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
13 April 2015
|
| In: |
Nature neuroscience
Year: 2015, Jahrgang: 18, Heft: 5, Pages: 666-673 |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/nn.3996 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nn.3996 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nn.3996 
|
| Verfasserangaben: | Jeremy Valluy, Silvia Bicker, Ayla Aksoy-Aksel, Martin Lackinger, Simon Sumer, Roberto Fiore, Tatjana Wüst, Dominik Seffer, Franziska Metge, Christoph Dieterich, Markus Wöhr, Rainer Schwarting, Gerhard Schratt |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1703819888 | ||
| 003 | DE-627 | ||
| 005 | 20220818142846.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200707s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/nn.3996 |2 doi | |
| 035 | |a (DE-627)1703819888 | ||
| 035 | |a (DE-599)KXP1703819888 | ||
| 035 | |a (OCoLC)1341344736 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Valluy, Jeremy Matthias |d 1984- |e VerfasserIn |0 (DE-588)1079933514 |0 (DE-627)842571337 |0 (DE-576)453085458 |4 aut | |
| 245 | 1 | 2 | |a A coding-independent function of an alternative Ube3a transcript during neuronal development |c Jeremy Valluy, Silvia Bicker, Ayla Aksoy-Aksel, Martin Lackinger, Simon Sumer, Roberto Fiore, Tatjana Wüst, Dominik Seffer, Franziska Metge, Christoph Dieterich, Markus Wöhr, Rainer Schwarting, Gerhard Schratt |
| 264 | 1 | |c 13 April 2015 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 07.07.2020 | ||
| 520 | |a This work shows a nocoding function of Ube3a1 RNA, an alternative transcript encoded by the Angelman syndrome gene Ube3a. Valluy et al. observe that Ube3a1 RNA competes with dendritic mRNAs for microRNAs, thereby regulating dendrite arborization and spine maturation of hippocampal neurons. These findings suggest a function for competing endogenous RNAs in synaptic development. | ||
| 700 | 1 | |a Bicker, Silvia |e VerfasserIn |0 (DE-588)106035344X |0 (DE-627)799491802 |0 (DE-576)416440967 |4 aut | |
| 700 | 1 | |a Aksoy Aksel, Ayla |d 1979- |e VerfasserIn |0 (DE-588)143249630 |0 (DE-627)644351039 |0 (DE-576)335856233 |4 aut | |
| 700 | 1 | |a Lackinger, Martin |e VerfasserIn |0 (DE-588)1194963528 |0 (DE-627)1677153156 |4 aut | |
| 700 | 1 | |a Sumer, Simon |d 1989- |e VerfasserIn |0 (DE-588)1149261080 |0 (DE-627)1009583948 |0 (DE-576)496608401 |4 aut | |
| 700 | 1 | |a Fiore, Roberto |d 1972- |e VerfasserIn |0 (DE-588)124868258 |0 (DE-627)36723291X |0 (DE-576)294542787 |4 aut | |
| 700 | 1 | |a Wüst, Tatjana |e VerfasserIn |0 (DE-588)1213302935 |0 (DE-627)1703818660 |4 aut | |
| 700 | 1 | |a Seffer, Dominik |d 1981- |e VerfasserIn |0 (DE-588)1076832326 |0 (DE-627)835375242 |0 (DE-576)445708018 |4 aut | |
| 700 | 1 | |a Metge, Franziska |e VerfasserIn |0 (DE-588)1164456695 |0 (DE-627)1028883420 |0 (DE-576)50876968X |4 aut | |
| 700 | 1 | |a Dieterich, Christoph |d 1975- |e VerfasserIn |0 (DE-588)130054844 |0 (DE-627)494359269 |0 (DE-576)297972448 |4 aut | |
| 700 | 1 | |a Wöhr, Markus |d 1980- |e VerfasserIn |0 (DE-588)136353606 |0 (DE-627)581097491 |0 (DE-576)300977344 |4 aut | |
| 700 | 1 | |a Schwarting, Rainer |d 1955- |e VerfasserIn |0 (DE-588)1209416115 |0 (DE-627)1696990696 |4 aut | |
| 700 | 1 | |a Schratt, Gerhard |d 1972- |e VerfasserIn |0 (DE-588)129269344 |0 (DE-627)391873490 |0 (DE-576)184974690 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature neuroscience |d New York, NY : Nature America, 1998 |g 18(2015), 5, Seite 666-673 |h Online-Ressource |w (DE-627)303393823 |w (DE-600)1494955-6 |w (DE-576)080887201 |x 1546-1726 |7 nnas |a A coding-independent function of an alternative Ube3a transcript during neuronal development |
| 773 | 1 | 8 | |g volume:18 |g year:2015 |g number:5 |g pages:666-673 |g extent:8 |a A coding-independent function of an alternative Ube3a transcript during neuronal development |
| 856 | 4 | 0 | |u https://doi.org/10.1038/nn.3996 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/nn.3996 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200707 | ||
| 993 | |a Article | ||
| 994 | |a 2015 | ||
| 998 | |g 1213302935 |a Wüst, Tatjana |m 1213302935:Wüst, Tatjana |d 500000 |d 500488 |e 500000PW1213302935 |e 500488PW1213302935 |k 0/500000/ |k 1/500000/500488/ |p 7 | ||
| 999 | |a KXP-PPN1703819888 |e 3696059307 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"title":[{"title_sort":"coding-independent function of an alternative Ube3a transcript during neuronal development","title":"A coding-independent function of an alternative Ube3a transcript during neuronal development"}],"physDesc":[{"extent":"8 S."}],"note":["Gesehen am 07.07.2020"],"name":{"displayForm":["Jeremy Valluy, Silvia Bicker, Ayla Aksoy-Aksel, Martin Lackinger, Simon Sumer, Roberto Fiore, Tatjana Wüst, Dominik Seffer, Franziska Metge, Christoph Dieterich, Markus Wöhr, Rainer Schwarting, Gerhard Schratt"]},"person":[{"given":"Jeremy Matthias","family":"Valluy","display":"Valluy, Jeremy Matthias","role":"aut"},{"given":"Silvia","role":"aut","display":"Bicker, Silvia","family":"Bicker"},{"given":"Ayla","role":"aut","family":"Aksoy Aksel","display":"Aksoy Aksel, Ayla"},{"role":"aut","family":"Lackinger","display":"Lackinger, Martin","given":"Martin"},{"given":"Simon","family":"Sumer","display":"Sumer, Simon","role":"aut"},{"display":"Fiore, Roberto","family":"Fiore","role":"aut","given":"Roberto"},{"role":"aut","family":"Wüst","display":"Wüst, Tatjana","given":"Tatjana"},{"role":"aut","display":"Seffer, Dominik","family":"Seffer","given":"Dominik"},{"given":"Franziska","family":"Metge","display":"Metge, Franziska","role":"aut"},{"role":"aut","display":"Dieterich, Christoph","family":"Dieterich","given":"Christoph"},{"role":"aut","display":"Wöhr, Markus","family":"Wöhr","given":"Markus"},{"role":"aut","family":"Schwarting","display":"Schwarting, Rainer","given":"Rainer"},{"given":"Gerhard","display":"Schratt, Gerhard","family":"Schratt","role":"aut"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"relHost":[{"note":["Gesehen am 02.03.05"],"title":[{"title":"Nature neuroscience","title_sort":"Nature neuroscience"}],"language":["eng"],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisher":"Nature America","dateIssuedKey":"1998","dateIssuedDisp":"1998-","publisherPlace":"New York, NY"}],"id":{"issn":["1546-1726"],"zdb":["1494955-6"],"eki":["303393823"]},"pubHistory":["1.1998 -"],"disp":"A coding-independent function of an alternative Ube3a transcript during neuronal developmentNature neuroscience","part":{"year":"2015","extent":"8","issue":"5","text":"18(2015), 5, Seite 666-673","pages":"666-673","volume":"18"},"recId":"303393823","titleAlt":[{"title":"Neuroscience"}],"type":{"media":"Online-Ressource","bibl":"periodical"}}],"origin":[{"dateIssuedKey":"2015","dateIssuedDisp":"13 April 2015"}],"recId":"1703819888","id":{"eki":["1703819888"],"doi":["10.1038/nn.3996"]}} | ||
| SRT | |a VALLUYJERECODINGINDE1320 | ||