KIT mutation and loss of 14q may be sufficient for the development of clinically symptomatic very low-risk GIST
The aim of this study was to determine the minimal set of genetic alterations required for the development of a very low risk clinically symptomatic gastro-intestinal stromal tumour within the stomach wall. We studied the genome of a very low-risk gastric gastro-intestinal stromal tumour by whole-ge...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
June 23, 2015
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| In: |
PLOS ONE
Year: 2015, Jahrgang: 10, Heft: 6 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0130149 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1371/journal.pone.0130149 Verlag, lizenzpflichtig, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130149 
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| Verfasserangaben: | Olaf Karl Klinke, Tuba Mizani, Gouri Baldwin, Brigitte Bancel, Mojgan Devouassoux-Shisheboran, Jean-Yves Scoazec, Pierre-Paul Bringuier, Regina Feederle, Anna Jauch, Katrin Hinderhofer, Philippe Taniere, Henri-Jacques Delecluse |
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| 520 | |a The aim of this study was to determine the minimal set of genetic alterations required for the development of a very low risk clinically symptomatic gastro-intestinal stromal tumour within the stomach wall. We studied the genome of a very low-risk gastric gastro-intestinal stromal tumour by whole-genome sequencing, comparative genomic hybridisation and methylation profiling. | ||
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