Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis
Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) have a similar clinical phenotype but represent distinct diseases, requiring different therapies. MicroRNAs (miRNAs) are short non-coding RNAs whose expression profiles can serve as diagnostic biomarkers and which may be invo...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 October 2015
|
| In: |
Journal of neuroinflammation
Year: 2015, Jahrgang: 12, Heft: 1 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/s12974-015-0418-1 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12974-015-0418-1
|
| Verfasserangaben: | Andreas Keller, Petra Leidinger, Eckart Meese, Jan Haas, Christina Backes, Ludwig Rasche, Janina R. Behrens, Catherina Pfuhl, Katharina Wakonig, René M. Gieß, Sven Jarius, Benjamin Meder, Judith Bellmann-Strobl, Friedemann Paul, Florence C. Pache and Klemens Ruprecht |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1724624865 | ||
| 003 | DE-627 | ||
| 005 | 20230427070019.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200714s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/s12974-015-0418-1 |2 doi | |
| 035 | |a (DE-627)1724624865 | ||
| 035 | |a (DE-599)KXP1724624865 | ||
| 035 | |a (OCoLC)1341345359 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Keller, Andreas |e VerfasserIn |0 (DE-588)1063131588 |0 (DE-627)810615657 |0 (DE-576)420468226 |4 aut | |
| 245 | 1 | 0 | |a Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis |c Andreas Keller, Petra Leidinger, Eckart Meese, Jan Haas, Christina Backes, Ludwig Rasche, Janina R. Behrens, Catherina Pfuhl, Katharina Wakonig, René M. Gieß, Sven Jarius, Benjamin Meder, Judith Bellmann-Strobl, Friedemann Paul, Florence C. Pache and Klemens Ruprecht |
| 264 | 1 | |c 31 October 2015 | |
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 17.07.2020 | ||
| 520 | |a Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) have a similar clinical phenotype but represent distinct diseases, requiring different therapies. MicroRNAs (miRNAs) are short non-coding RNAs whose expression profiles can serve as diagnostic biomarkers and which may be involved in the pathophysiology of neuroinflammatory diseases. Here, we analyzed miRNA profiles in serum and whole blood of patients with NMOSD and clinically isolated syndrome (CIS)/relapsing-remitting MS (RRMS) as well as healthy controls by next-generation sequencing (NGS). | ||
| 700 | 1 | |a Haas, Jan |e VerfasserIn |0 (DE-588)1030297231 |0 (DE-627)735001251 |0 (DE-576)378095706 |4 aut | |
| 700 | 1 | |a Jarius, Sven |e VerfasserIn |0 (DE-588)1054615918 |0 (DE-627)791654818 |0 (DE-576)410367478 |4 aut | |
| 700 | 1 | |a Meder, Benjamin |e VerfasserIn |0 (DE-588)135821630 |0 (DE-627)571676316 |0 (DE-576)300664745 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of neuroinflammation |d London : BioMed Central, 2004 |g 12(2015) Artikel-Nummer 196, 12 Seiten |h Online-Ressource |w (DE-627)391784781 |w (DE-600)2156455-3 |w (DE-576)12192985X |x 1742-2094 |7 nnas |a Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis |
| 773 | 1 | 8 | |g volume:12 |g year:2015 |g number:1 |g extent:12 |a Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis |
| 856 | 4 | 0 | |u https://doi.org/10.1186/s12974-015-0418-1 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200714 | ||
| 993 | |a Article | ||
| 994 | |a 2015 | ||
| 998 | |g 135821630 |a Meder, Benjamin |m 135821630:Meder, Benjamin |d 910000 |d 910100 |e 910000PM135821630 |e 910100PM135821630 |k 0/910000/ |k 1/910000/910100/ |p 12 | ||
| 998 | |g 1054615918 |a Jarius, Sven |m 1054615918:Jarius, Sven |d 910000 |d 911100 |e 910000PJ1054615918 |e 911100PJ1054615918 |k 0/910000/ |k 1/910000/911100/ |p 11 | ||
| 998 | |g 1030297231 |a Haas, Jan |m 1030297231:Haas, Jan |d 910000 |d 910100 |e 910000PH1030297231 |e 910100PH1030297231 |k 0/910000/ |k 1/910000/910100/ |p 4 | ||
| 999 | |a KXP-PPN1724624865 |e 3724101074 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis","title_sort":"Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis"}],"physDesc":[{"extent":"12 S."}],"relHost":[{"origin":[{"publisher":"BioMed Central","publisherPlace":"London","dateIssuedKey":"2004","dateIssuedDisp":"2004-"}],"disp":"Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosisJournal of neuroinflammation","type":{"bibl":"periodical","media":"Online-Ressource"},"id":{"zdb":["2156455-3"],"eki":["391784781"],"issn":["1742-2094"]},"recId":"391784781","language":["eng"],"titleAlt":[{"title":"JNI"}],"pubHistory":["1.2004 -"],"note":["Gesehen am 12.07.10"],"part":{"issue":"1","volume":"12","year":"2015","text":"12(2015) Artikel-Nummer 196, 12 Seiten","extent":"12"},"title":[{"title":"Journal of neuroinflammation","title_sort":"Journal of neuroinflammation","subtitle":"JNI"}],"physDesc":[{"extent":"Online-Ressource"}]}],"person":[{"display":"Keller, Andreas","role":"aut","family":"Keller","given":"Andreas"},{"role":"aut","family":"Haas","display":"Haas, Jan","given":"Jan"},{"given":"Sven","display":"Jarius, Sven","family":"Jarius","role":"aut"},{"given":"Benjamin","display":"Meder, Benjamin","family":"Meder","role":"aut"}],"language":["eng"],"note":["Gesehen am 17.07.2020"],"origin":[{"dateIssuedKey":"2015","dateIssuedDisp":"31 October 2015"}],"name":{"displayForm":["Andreas Keller, Petra Leidinger, Eckart Meese, Jan Haas, Christina Backes, Ludwig Rasche, Janina R. Behrens, Catherina Pfuhl, Katharina Wakonig, René M. Gieß, Sven Jarius, Benjamin Meder, Judith Bellmann-Strobl, Friedemann Paul, Florence C. Pache and Klemens Ruprecht"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"doi":["10.1186/s12974-015-0418-1"],"eki":["1724624865"]},"recId":"1724624865"} | ||
| SRT | |a KELLERANDRNEXTGENERA3120 | ||