In vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography
Transthyretin familial amyloid polyneuropathy is a rare, autosomal-dominant inherited multisystem disorder usually manifesting with a rapidly progressive, axonal, distally-symmetric polyneuropathy. The detection of nerve injury by nerve conduction studies is limited, due to preferential involvement...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2015
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| In: |
Brain
Year: 2014, Jahrgang: 138, Heft: 3, Pages: 549-562 |
| ISSN: | 1460-2156 |
| DOI: | 10.1093/brain/awu344 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/brain/awu344 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/brain/article/138/3/549/332291 
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| Verfasserangaben: | Jennifer Kollmer, Ernst Hund, Benjamin Hornung, Ute Hegenbart, Stefan O. Schönland, Christoph Kimmich, Arnt V. Kristen, Jan Purrucker, Christoph Röcken, Sabine Heiland, Martin Bendszus and Mirko Pham |
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| 520 | |a Transthyretin familial amyloid polyneuropathy is a rare, autosomal-dominant inherited multisystem disorder usually manifesting with a rapidly progressive, axonal, distally-symmetric polyneuropathy. The detection of nerve injury by nerve conduction studies is limited, due to preferential involvement of small-fibres in early stages. We investigated whether lower limb nerve-injury can be detected, localized and quantified in vivo by high-resolution magnetic resonance neurography. | ||
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