Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism
AbstractObjective. The development of RA is linked to local infiltration of immune cells and to changes in the phenotype of synovial fibroblasts. Synovial fibr
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2020
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| In: |
Rheumatology
Year: 2019, Volume: 59, Issue: 5, Pages: 1148-1158 |
| ISSN: | 1462-0332 |
| DOI: | 10.1093/rheumatology/kez587 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/rheumatology/kez587 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/rheumatology/article/59/5/1148/5679821 |
| Author Notes: | Nathalie-Christin Kaul, Soumya R. Mohapatra, Isabell Adam, Christine Tucher, Theresa Tretter, Christiane A. Opitz, Hanns-Martin Lorenz and Lars-Oliver Tykocinski |
| Summary: | AbstractObjective. The development of RA is linked to local infiltration of immune cells and to changes in the phenotype of synovial fibroblasts. Synovial fibr |
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| Item Description: | Advance access publication 17 December 2019 Gesehen am 17.07.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1462-0332 |
| DOI: | 10.1093/rheumatology/kez587 |