Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism

AbstractObjective. The development of RA is linked to local infiltration of immune cells and to changes in the phenotype of synovial fibroblasts. Synovial fibr

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Bibliographic Details
Main Authors: Kaul, Nathalie-Christin (Author) , Mohapatra, Soumya R. (Author) , Adam, Isabell (Author) , Tucher, Christine (Author) , Tretter, Theresa (Author) , Opitz, Christiane (Author) , Lorenz, Hanns-Martin (Author) , Tykocinski, Lars-Oliver (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Rheumatology
Year: 2019, Volume: 59, Issue: 5, Pages: 1148-1158
ISSN:1462-0332
DOI:10.1093/rheumatology/kez587
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/rheumatology/kez587
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/rheumatology/article/59/5/1148/5679821
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Author Notes:Nathalie-Christin Kaul, Soumya R. Mohapatra, Isabell Adam, Christine Tucher, Theresa Tretter, Christiane A. Opitz, Hanns-Martin Lorenz and Lars-Oliver Tykocinski
Description
Summary:AbstractObjective. The development of RA is linked to local infiltration of immune cells and to changes in the phenotype of synovial fibroblasts. Synovial fibr
Item Description:Advance access publication 17 December 2019
Gesehen am 17.07.2020
Physical Description:Online Resource
ISSN:1462-0332
DOI:10.1093/rheumatology/kez587