Current use of metformin in addition to insulin in pediatric patients with type 1 diabetes mellitus: an analysis based on a large diabetes registry in Germany and Austria
With increasing obesity in childhood and adolescence, weight gain, and insulin resistance become also more frequent in patients with type 1 diabetes mellitus (T1DM). Especially during puberty, insulin therapy often has to be intensified and higher insulin doses are necessary. Some studies point to a...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2015
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| In: |
Pediatric diabetes
Year: 2014, Jahrgang: 16, Heft: 7, Pages: 529-537 |
| ISSN: | 1399-5448 |
| DOI: | 10.1111/pedi.12203 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1111/pedi.12203 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.12203 
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| Verfasserangaben: | Katja Konrad, Nicolin Datz, Ilse Engelsberger, Jürgen Grulich‐Henn, Thomas Hoertenhuber, Burkhild Knauth, Thomas Meissner, Susanna Wiegand, Joachim Woelfle, Reinhard W. Holl |
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| 245 | 1 | 0 | |a Current use of metformin in addition to insulin in pediatric patients with type 1 diabetes mellitus |b an analysis based on a large diabetes registry in Germany and Austria |c Katja Konrad, Nicolin Datz, Ilse Engelsberger, Jürgen Grulich‐Henn, Thomas Hoertenhuber, Burkhild Knauth, Thomas Meissner, Susanna Wiegand, Joachim Woelfle, Reinhard W. Holl |
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| 520 | |a With increasing obesity in childhood and adolescence, weight gain, and insulin resistance become also more frequent in patients with type 1 diabetes mellitus (T1DM). Especially during puberty, insulin therapy often has to be intensified and higher insulin doses are necessary. Some studies point to a beneficial effect of metformin in addition to insulin in these patients. In order to describe current practice and possible benefits, we compared pediatric T1DM patients with insulin plus metformin (n = 525) to patients with insulin therapy only (n = 57 487) in a prospective multicenter analysis. | ||
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