Buchumschlag

Serum vitamin D levels and hypogonadism in men

There is inconsistent evidence on a possible association of vitamin D and androgen levels in men. We therefore aim to investigate the association of 25-hydroxyvitamin D (25(OH)D) with androgen levels in a cohort of middle-aged men. This cross-sectional study included 225 men with a median (interquar...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lerchbaum, Elisabeth (VerfasserIn) , Pilz, S. (VerfasserIn) , Trummer, C. (VerfasserIn) , Rabe, Thomas (VerfasserIn) , Schenk, M. (VerfasserIn) , Heijboer, A. C. (VerfasserIn) , Obermayer‐Pietsch, B. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 16 July 2014
In: Andrology
Year: 2014, Jahrgang: 2, Heft: 5, Pages: 748-754
ISSN:2047-2927
DOI:10.1111/j.2047-2927.2014.00247.x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.2047-2927.2014.00247.x
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.2047-2927.2014.00247.x
Volltext
Verfasserangaben:E. Lerchbaum, S. Pilz, C. Trummer, T. Rabe, M. Schenk, A.C. Heijboer and B. Obermayer‐Pietsch

MARC

LEADER 00000caa a2200000 c 4500
001 1725358042
003 DE-627
005 20220818155751.0
007 cr uuu---uuuuu
008 200723s2014 xx |||||o 00| ||eng c
024 7 |a 10.1111/j.2047-2927.2014.00247.x  |2 doi 
035 |a (DE-627)1725358042 
035 |a (DE-599)KXP1725358042 
035 |a (OCoLC)1341347732 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Lerchbaum, Elisabeth  |e VerfasserIn  |0 (DE-588)1068937459  |0 (DE-627)821074288  |0 (DE-576)428312543  |4 aut 
245 1 0 |a Serum vitamin D levels and hypogonadism in men  |c E. Lerchbaum, S. Pilz, C. Trummer, T. Rabe, M. Schenk, A.C. Heijboer and B. Obermayer‐Pietsch 
264 1 |c 16 July 2014 
300 |a 7 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 23.07.2020 
520 |a There is inconsistent evidence on a possible association of vitamin D and androgen levels in men. We therefore aim to investigate the association of 25-hydroxyvitamin D (25(OH)D) with androgen levels in a cohort of middle-aged men. This cross-sectional study included 225 men with a median (interquartile range) age of 35 (30-41) years. We measured 25(OH)D, total testosterone (TT) and SHBG concentrations. Hypogonadism was defined as TT <10.4 nmol/L. We found no significant correlation of 25(OH)D and androgen levels. Furthermore, androgen levels were not significantly different across 25(OH)D quintiles. The overall prevalence of hypogonadism was 21.5% and lowest in men within 25(OH)D quintile 4 (82-102 nmol/L). We found a significantly increased risk of hypogonadism in men within the highest 25(OH)D quintile (>102 nmol/L) compared to men in quintile 4 (reference) in crude (OR 5.10, 1.51-17.24, p = 0.009) as well as in multivariate adjusted analysis (OR 9.21, 2.27-37.35, p = 0.002). We found a trend towards increased risk of hypogonadism in men within the lowest 25(OH)D quintile (≤43.9 nmol/L). In conclusion, our data suggest that men with very high 25(OH)D levels (>102 nmol/L) might be at an increased risk of hypogonadism. Furthermore, we observed a trend towards increased risk of hypogonadism in men with very low vitamin D levels indicating a U-shaped association of vitamin D levels and hypogonadism. With respect to risk of male hypogonadism, our results suggest optimal serum 25(OH)D concentrations of 82-102 nmol/L. 
650 4 |a androgens 
650 4 |a hypogonadism 
650 4 |a sex hormones 
700 1 |a Pilz, S.  |e VerfasserIn  |4 aut 
700 1 |a Trummer, C.  |e VerfasserIn  |4 aut 
700 1 |a Rabe, Thomas  |d 1951-  |e VerfasserIn  |0 (DE-588)120341654  |0 (DE-627)080614795  |0 (DE-576)166163465  |4 aut 
700 1 |a Schenk, M.  |e VerfasserIn  |4 aut 
700 1 |a Heijboer, A. C.  |e VerfasserIn  |4 aut 
700 1 |a Obermayer‐Pietsch, B.  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Andrology  |d Oxford [u.a.] : Wiley-Blackwell, 2013  |g 2(2014), 5, Seite 748-754  |h Online-Ressource  |w (DE-627)731886534  |w (DE-600)2693844-3  |w (DE-576)378914847  |x 2047-2927  |7 nnas  |a Serum vitamin D levels and hypogonadism in men 
773 1 8 |g volume:2  |g year:2014  |g number:5  |g pages:748-754  |g extent:7  |a Serum vitamin D levels and hypogonadism in men 
856 4 0 |u https://doi.org/10.1111/j.2047-2927.2014.00247.x  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://onlinelibrary.wiley.com/doi/abs/10.1111/j.2047-2927.2014.00247.x  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20200723 
993 |a Article 
994 |a 2014 
998 |g 120341654  |a Rabe, Thomas  |m 120341654:Rabe, Thomas  |d 910000  |d 910400  |e 910000PR120341654  |e 910400PR120341654  |k 0/910000/  |k 1/910000/910400/  |p 4 
998 |g 1068937459  |a Lerchbaum, Elisabeth  |m 1068937459:Lerchbaum, Elisabeth  |p 1  |x j 
999 |a KXP-PPN1725358042  |e 3728789062 
BIB |a Y 
SER |a journal 
JSO |a {"person":[{"role":"aut","display":"Lerchbaum, Elisabeth","roleDisplay":"VerfasserIn","given":"Elisabeth","family":"Lerchbaum"},{"given":"S.","family":"Pilz","role":"aut","roleDisplay":"VerfasserIn","display":"Pilz, S."},{"given":"C.","family":"Trummer","role":"aut","roleDisplay":"VerfasserIn","display":"Trummer, C."},{"given":"Thomas","family":"Rabe","role":"aut","roleDisplay":"VerfasserIn","display":"Rabe, Thomas"},{"given":"M.","family":"Schenk","role":"aut","roleDisplay":"VerfasserIn","display":"Schenk, M."},{"roleDisplay":"VerfasserIn","display":"Heijboer, A. C.","role":"aut","family":"Heijboer","given":"A. C."},{"display":"Obermayer‐Pietsch, B.","roleDisplay":"VerfasserIn","role":"aut","family":"Obermayer‐Pietsch","given":"B."}],"title":[{"title":"Serum vitamin D levels and hypogonadism in men","title_sort":"Serum vitamin D levels and hypogonadism in men"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 23.07.2020"],"language":["eng"],"recId":"1725358042","name":{"displayForm":["E. Lerchbaum, S. Pilz, C. Trummer, T. Rabe, M. Schenk, A.C. Heijboer and B. Obermayer‐Pietsch"]},"origin":[{"dateIssuedKey":"2014","dateIssuedDisp":"16 July 2014"}],"id":{"doi":["10.1111/j.2047-2927.2014.00247.x"],"eki":["1725358042"]},"physDesc":[{"extent":"7 S."}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"2013-","dateIssuedKey":"2013","publisher":"Wiley-Blackwell","publisherPlace":"Oxford [u.a.]"}],"id":{"issn":["2047-2927"],"zdb":["2693844-3"],"eki":["731886534"],"doi":["10.1111/(ISSN)2047-2927"]},"name":{"displayForm":["American Society of Andrology ; European Academy of Andrology"]},"pubHistory":["1.2013 -"],"part":{"year":"2014","pages":"748-754","issue":"5","volume":"2","text":"2(2014), 5, Seite 748-754","extent":"7"},"note":["Gesehen am 04.01.2013"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Serum vitamin D levels and hypogonadism in menAndrology","language":["eng"],"recId":"731886534","title":[{"title":"Andrology","title_sort":"Andrology"}]}]} 
SRT |a LERCHBAUMESERUMVITAM1620 

Ähnliche Einträge