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Identification of cis-regulatory modules encoding temporal dynamics during development

Developmental transcriptional regulatory networks are circuits of transcription factors (TFs) and cis-acting DNA elements (Cis Regulatory Modules, CRMs) that dynamically control expression of downstream genes. Comprehensive knowledge of these networks is an essential step towards our understanding o...

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Bibliographische Detailangaben
Hauptverfasser: Potier, Delphine (VerfasserIn) , Seyres, Denis (VerfasserIn) , Guichard, Céline (VerfasserIn) , Iche-Torres, Magali (VerfasserIn) , Aerts, Stein (VerfasserIn) , Herrmann, Carl (VerfasserIn) , Perrin, Laurent (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 27 June 2014
In: BMC genomics
Year: 2014, Jahrgang: 15
ISSN:1471-2164
DOI:10.1186/1471-2164-15-534
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2164-15-534
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Verfasserangaben:Delphine Potier, Denis Seyres, Céline Guichard, Magali Iche-Torres, Stein Aerts, Carl Herrmann and Laurent Perrin
Beschreibung
Zusammenfassung:Developmental transcriptional regulatory networks are circuits of transcription factors (TFs) and cis-acting DNA elements (Cis Regulatory Modules, CRMs) that dynamically control expression of downstream genes. Comprehensive knowledge of these networks is an essential step towards our understanding of developmental processes. However, this knowledge is mostly based on genome-wide mapping of transcription factor binding sites, and therefore requires prior knowledge regarding the TFs involved in the network.
Beschreibung:Gesehen am 23.07.2020
Beschreibung:Online Resource
ISSN:1471-2164
DOI:10.1186/1471-2164-15-534

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