Einblicke in die Kinderstube der Ribosomen
Ribosome formation can be imagined like an assembly line for automobile production. Pre-ribosomes transit through a number of ‘mounting-stages’. These different steps are catalyzed by about 200 assembly factors that bind transiently to the evolving ribosome. However, it currently remains unclear how...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | German |
| Published: |
27 March 2015
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| In: |
Biospektrum
Year: 2015, Volume: 21, Issue: 2, Pages: 144-147 |
| ISSN: | 1868-6249 |
| DOI: | 10.1007/s12268-015-0549-z |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s12268-015-0549-z
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| Author Notes: | Jochen Baßler, Ed Hurt |
| Summary: | Ribosome formation can be imagined like an assembly line for automobile production. Pre-ribosomes transit through a number of ‘mounting-stages’. These different steps are catalyzed by about 200 assembly factors that bind transiently to the evolving ribosome. However, it currently remains unclear how this myriad of factors can trigger ribosome synthesis. Insight into the mechanism of ribosome biogenesis also has medical relevance, since there are diseases in which ribosome assembly is disturbed. |
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| Item Description: | Gesehen am 03.08.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1868-6249 |
| DOI: | 10.1007/s12268-015-0549-z |