UV-induced tetrazole-thiol reaction for polymer conjugation and surface functionalization

A UV-induced 1,3-dipolar nucleophilic addition of tetrazoles to thiols is described. Under UV irradiation the reaction proceeds rapidly at room temperature, with high yields, without a catalyst, and in both polar protic and aprotic solvents, including water. This UV-induced tetrazole-thiol reaction...

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Main Authors: Feng, Wenqian (Author) , Li, Linxian (Author) , Yang, Chengwu (Author) , Welle, Alexander (Author) , Trapp, Oliver (Author) , Levkin, Pavel A. (Author)
Format: Article (Journal)
Language:English
Published: June 8, 2015
In: Angewandte Chemie. International edition
Year: 2015, Volume: 54, Issue: 30, Pages: 8732-8735
ISSN:1521-3773
DOI:10.1002/anie.201502954
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/anie.201502954
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201502954
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Author Notes:Wenqian Feng, Linxian Li, Chengwu Yang, Alexander Welle, Oliver Trapp, and Pavel A. Levkin

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