Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging

Fluorescent Si-rhodamines were modified to enable complexation with the Re(i)- and 99mTc(i)-tricarbonyl core. The corresponding complexes exhibit suitable properties as bimodal imaging probes for SPECT- and optical imaging in vitro. Importantly, the novel in- aqueous-solution-stable, functionalized...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kanagasundaram, Thines (VerfasserIn) , Kramer, Carsten Sven (VerfasserIn) , Boros, Eszter (VerfasserIn) , Kopka, Klaus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: June 14, 2020
In: Dalton transactions
Year: 2020, Jahrgang: 49, Heft: 22, Pages: 7294-7298
ISSN:1477-9234
DOI:10.1039/d0dt01084g
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/d0dt01084g
Volltext
Verfasserangaben:Thines Kanagasundaram, Carsten S. Kramer, Eszter Boros and Klaus Kopka

MARC

LEADER 00000caa a2200000 c 4500
001 1726831531
003 DE-627
005 20230427082126.0
007 cr uuu---uuuuu
008 200812s2020 xx |||||o 00| ||eng c
024 7 |a 10.1039/d0dt01084g  |2 doi 
035 |a (DE-627)1726831531 
035 |a (DE-599)KXP1726831531 
035 |a (OCoLC)1341354898 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 30  |2 sdnb 
100 1 |a Kanagasundaram, Thines  |d 1993-  |e VerfasserIn  |0 (DE-588)117231652X  |0 (DE-627)1041122977  |0 (DE-576)514511435  |4 aut 
245 1 0 |a Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging  |c Thines Kanagasundaram, Carsten S. Kramer, Eszter Boros and Klaus Kopka 
264 1 |c June 14, 2020 
300 |a 5 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 12.08.2020 
520 |a Fluorescent Si-rhodamines were modified to enable complexation with the Re(i)- and 99mTc(i)-tricarbonyl core. The corresponding complexes exhibit suitable properties as bimodal imaging probes for SPECT- and optical imaging in vitro. Importantly, the novel in- aqueous-solution-stable, functionalized Si-rhodamines retain favourable optical properties after complexation (QY = 0.09, λabs = 654 nm, λem = 669 nm in PBS) and show promising near-infrared optical properties for potential in vivo applications enabling bimodal scintigraphic imaging and optical imaging, e.g. used in radio- and fluorescence-guided tumour resection. 
700 1 |a Kramer, Carsten Sven  |d 1983-  |e VerfasserIn  |0 (DE-588)105032367X  |0 (DE-627)783852673  |0 (DE-576)404525229  |4 aut 
700 1 |a Boros, Eszter  |e VerfasserIn  |4 aut 
700 1 |a Kopka, Klaus  |d 1968-  |e VerfasserIn  |0 (DE-588)173031862  |0 (DE-627)69795661X  |0 (DE-576)133884724  |4 aut 
773 0 8 |i Enthalten in  |t Dalton transactions  |d Cambridge : Royal Society of Chemistry, 2003  |g 49(2020), 22, Seite 7294-7298  |h Online-Ressource  |w (DE-627)268759146  |w (DE-600)1472887-4  |w (DE-576)077609883  |x 1477-9234  |7 nnas  |a Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging 
773 1 8 |g volume:49  |g year:2020  |g number:22  |g pages:7294-7298  |g extent:5  |a Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging 
856 4 0 |u https://doi.org/10.1039/d0dt01084g  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20200812 
993 |a Article 
994 |a 2020 
998 |g 105032367X  |a Kramer, Carsten Sven  |m 105032367X:Kramer, Carsten Sven  |d 120000  |e 120000PK105032367X  |k 0/120000/  |p 2 
998 |g 117231652X  |a Kanagasundaram, Thines  |m 117231652X:Kanagasundaram, Thines  |d 120000  |e 120000PK117231652X  |k 0/120000/  |p 1  |x j 
999 |a KXP-PPN1726831531  |e 3738595147 
BIB |a Y 
SER |a journal 
JSO |a {"origin":[{"dateIssuedKey":"2020","dateIssuedDisp":"June 14, 2020"}],"id":{"doi":["10.1039/d0dt01084g"],"eki":["1726831531"]},"name":{"displayForm":["Thines Kanagasundaram, Carsten S. Kramer, Eszter Boros and Klaus Kopka"]},"physDesc":[{"extent":"5 S."}],"relHost":[{"title":[{"subtitle":"a journal of inorganic chemistry, including bioinorganic, organometallic, and solid-state chemistry","title":"Dalton transactions","title_sort":"Dalton transactions"}],"part":{"year":"2020","pages":"7294-7298","issue":"22","text":"49(2020), 22, Seite 7294-7298","volume":"49","extent":"5"},"pubHistory":["2003, issue 1 (2003)-"],"corporate":[{"roleDisplay":"Herausgebendes Organ","display":"Royal Society of Chemistry","role":"isb"}],"language":["eng"],"recId":"268759146","type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imagingDalton transactions","note":["Gesehen am 30.01.25"],"id":{"issn":["1477-9234"],"zdb":["1472887-4"],"eki":["268759146"]},"origin":[{"dateIssuedKey":"2003","publisher":"Royal Society of Chemistry","dateIssuedDisp":"2003-","publisherPlace":"Cambridge"}],"name":{"displayForm":["Royal Society of Chemistry"]},"physDesc":[{"extent":"Online-Ressource"}]}],"title":[{"title":"Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging","title_sort":"Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging"}],"person":[{"role":"aut","display":"Kanagasundaram, Thines","roleDisplay":"VerfasserIn","given":"Thines","family":"Kanagasundaram"},{"display":"Kramer, Carsten Sven","roleDisplay":"VerfasserIn","role":"aut","family":"Kramer","given":"Carsten Sven"},{"roleDisplay":"VerfasserIn","display":"Boros, Eszter","role":"aut","family":"Boros","given":"Eszter"},{"family":"Kopka","given":"Klaus","roleDisplay":"VerfasserIn","display":"Kopka, Klaus","role":"aut"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 12.08.2020"],"recId":"1726831531","language":["eng"]} 
SRT |a KANAGASUNDRHENIUMAND1420