Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients

An imbalance between cell proliferation and programmed cell death can result in tumor growth. Although most systemic cytotoxic agents induce apoptosis in tumor cells, a high apoptotic rate in primary breast cancer correlates with poor prognosis. The aim of this study was to investigate the incidence...

Full description

Saved in:
Bibliographic Details
Main Authors: Krawczyk, Natalia (Author) , Hartkopf, Andreas (Author) , Banys, Malgorzata (Author) , Meier-Stiegen, Franziska (Author) , Staebler, Annette (Author) , Wallwiener, Markus (Author) , Röhm, Carmen (Author) , Hoffmann, Juergen (Author) , Hahn, Markus (Author) , Fehm, Tanja (Author)
Format: Article (Journal)
Language:English
Published: 3 June 2014
In: BMC cancer
Year: 2014, Volume: 14
ISSN:1471-2407
DOI:10.1186/1471-2407-14-394
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-14-394
Get full text
Author Notes:Natalia Krawczyk, Andreas Hartkopf, Malgorzata Banys, Franziska Meier-Stiegen, Annette Staebler, Markus Wallwiener, Carmen Röhm, Juergen Hoffmann, Markus Hahn and Tanja Fehm

MARC

LEADER 00000caa a2200000 c 4500
001 1726932958
003 DE-627
005 20250323005729.0
007 cr uuu---uuuuu
008 200812s2014 xx |||||o 00| ||eng c
024 7 |a 10.1186/1471-2407-14-394  |2 doi 
035 |a (DE-627)1726932958 
035 |a (DE-599)KXP1726932958 
035 |a (OCoLC)1341355112 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Krawczyk, Natalia  |d 1981-  |e VerfasserIn  |0 (DE-588)143124099  |0 (DE-627)64251402X  |0 (DE-576)335176003  |4 aut 
245 1 0 |a Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients  |c Natalia Krawczyk, Andreas Hartkopf, Malgorzata Banys, Franziska Meier-Stiegen, Annette Staebler, Markus Wallwiener, Carmen Röhm, Juergen Hoffmann, Markus Hahn and Tanja Fehm 
264 1 |c 3 June 2014 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 12.08.2020 
520 |a An imbalance between cell proliferation and programmed cell death can result in tumor growth. Although most systemic cytotoxic agents induce apoptosis in tumor cells, a high apoptotic rate in primary breast cancer correlates with poor prognosis. The aim of this study was to investigate the incidence and the prognostic significance of apoptotic disseminated tumor cells (DTC) in the bone marrow (BM) of breast cancer patients who either underwent primary surgery or primary systemic chemotherapy (PST). 
700 1 |a Hartkopf, Andreas  |e VerfasserIn  |4 aut 
700 1 |a Banys, Malgorzata  |e VerfasserIn  |4 aut 
700 1 |a Meier-Stiegen, Franziska  |e VerfasserIn  |4 aut 
700 1 |a Staebler, Annette  |e VerfasserIn  |4 aut 
700 1 |a Wallwiener, Markus  |d 1980-  |e VerfasserIn  |0 (DE-588)134044827  |0 (DE-627)692043934  |0 (DE-576)27468327X  |4 aut 
700 1 |a Röhm, Carmen  |e VerfasserIn  |4 aut 
700 1 |a Hoffmann, Juergen  |e VerfasserIn  |4 aut 
700 1 |a Hahn, Markus  |e VerfasserIn  |4 aut 
700 1 |8 1\p  |a Fehm, Tanja  |d 1971-  |e VerfasserIn  |0 (DE-588)120391759  |0 (DE-627)080645690  |0 (DE-576)292194064  |4 aut 
773 0 8 |i Enthalten in  |t BMC cancer  |d London : BioMed Central, 2001  |g 14(2014) Artikel-Nummer 394, 7 Seiten  |h Online-Ressource  |w (DE-627)326643710  |w (DE-600)2041352-X  |w (DE-576)107014645  |x 1471-2407  |7 nnas  |a Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients 
773 1 8 |g volume:14  |g year:2014  |a Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients 
856 4 0 |u https://doi.org/10.1186/1471-2407-14-394  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
883 |8 1\p  |a cgwrk  |d 20250301  |q DE-101  |u https://d-nb.info/provenance/plan#cgwrk 
951 |a AR 
992 |a 20200812 
993 |a Article 
994 |a 2014 
998 |g 134044827  |a Wallwiener, Markus  |m 134044827:Wallwiener, Markus  |d 910000  |d 910400  |e 910000PW134044827  |e 910400PW134044827  |k 0/910000/  |k 1/910000/910400/  |p 6 
999 |a KXP-PPN1726932958  |e 3738676260 
BIB |a Y 
SER |a journal 
JSO |a {"id":{"doi":["10.1186/1471-2407-14-394"],"eki":["1726932958"]},"title":[{"title_sort":"Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients","title":"Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patients"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedDisp":"3 June 2014","dateIssuedKey":"2014"}],"relHost":[{"disp":"Prognostic relevance of induced and spontaneous apoptosis of disseminated tumor cells in primary breast cancer patientsBMC cancer","type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["1.2001 -"],"note":["Gesehen am 22.05.20"],"part":{"volume":"14","year":"2014","text":"14(2014) Artikel-Nummer 394, 7 Seiten"},"language":["eng"],"origin":[{"dateIssuedDisp":"2001-","publisher":"BioMed Central ; Springer","publisherPlace":"London ; Berlin ; Heidelberg","dateIssuedKey":"2001"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["2041352-X"],"issn":["1471-2407"],"eki":["326643710"]},"title":[{"title":"BMC cancer","title_sort":"BMC cancer"}],"recId":"326643710"}],"language":["eng"],"name":{"displayForm":["Natalia Krawczyk, Andreas Hartkopf, Malgorzata Banys, Franziska Meier-Stiegen, Annette Staebler, Markus Wallwiener, Carmen Röhm, Juergen Hoffmann, Markus Hahn and Tanja Fehm"]},"note":["Gesehen am 12.08.2020"],"person":[{"family":"Krawczyk","role":"aut","given":"Natalia","display":"Krawczyk, Natalia"},{"display":"Hartkopf, Andreas","given":"Andreas","family":"Hartkopf","role":"aut"},{"family":"Banys","role":"aut","given":"Malgorzata","display":"Banys, Malgorzata"},{"display":"Meier-Stiegen, Franziska","given":"Franziska","role":"aut","family":"Meier-Stiegen"},{"family":"Staebler","role":"aut","given":"Annette","display":"Staebler, Annette"},{"role":"aut","family":"Wallwiener","given":"Markus","display":"Wallwiener, Markus"},{"given":"Carmen","display":"Röhm, Carmen","family":"Röhm","role":"aut"},{"given":"Juergen","display":"Hoffmann, Juergen","role":"aut","family":"Hoffmann"},{"role":"aut","family":"Hahn","given":"Markus","display":"Hahn, Markus"},{"given":"Tanja","display":"Fehm, Tanja","family":"Fehm","role":"aut"}],"recId":"1726932958"} 
SRT |a KRAWCZYKNAPROGNOSTIC3201