Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis: an analysis of NSS motor subscores
We aimed to study the correlations between gray matter volume and the motor subscores of NSS in first-episode psychosis patients with both, whole brain and region of interest analyses. The structural MRIs of 81 first-episode psychosis patients were analyzed by using voxel-based morphometry (VBM) for...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 March 2020
|
| In: |
Psychiatry research. Neuroimaging
Year: 2020, Jahrgang: 300, Pages: 1-8 |
| ISSN: | 1872-7506 |
| DOI: | 10.1016/j.pscychresns.2020.111067 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pscychresns.2020.111067 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0925492720300391 
|
| Verfasserangaben: | David Quispe Escudero, Christina J. Herold, Li Kong, Johannes Schröder |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 172696888X | ||
| 003 | DE-627 | ||
| 005 | 20220818173948.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200813s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.pscychresns.2020.111067 |2 doi | |
| 035 | |a (DE-627)172696888X | ||
| 035 | |a (DE-599)KXP172696888X | ||
| 035 | |a (OCoLC)1341355229 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Quispe Escudero, David |e VerfasserIn |0 (DE-588)1215850921 |0 (DE-627)1726970280 |4 aut | |
| 245 | 1 | 0 | |a Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis |b an analysis of NSS motor subscores |c David Quispe Escudero, Christina J. Herold, Li Kong, Johannes Schröder |
| 264 | 1 | |c 31 March 2020 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 13.08.2020 | ||
| 520 | |a We aimed to study the correlations between gray matter volume and the motor subscores of NSS in first-episode psychosis patients with both, whole brain and region of interest analyses. The structural MRIs of 81 first-episode psychosis patients were analyzed by using voxel-based morphometry (VBM) for SPM. NSS were assessed using the Heidelberg scale. Significant decreases of gray matter volume were correlated to high NSS total scores and, more specifically, frontal, subcortical and cerebellar areas were significantly correlated with increased scores of the subscores Motor Coordination (MoCo) and Complex Motor Tasks (CMT). When applying a stricter statistical correction, only the frontal gyrus and caudate nucleus survived for MoCo; whereas the precentral and superior frontal gyri survived for CMT. When doing regional analyses, using as masks the structures deemed as significant by the whole brain analyses and applying the FWE-correction, the superior frontal gyrus, thalamus and caudate nucleus correlated negatively with MoCo; and the precentral and superior frontal gyri, thalamus and caudate nucleus showed inverse correlations with CMT. These results suggest that cerebral cortex, subcortical structures (thalamus and striatum) and cerebellum are inversely correlated to both motor NSS subscores, the first time a study describes this relationship for all the relevant structures simultaneously. For its part, ROI proves to be effective demonstrating that subcortical structures (thalamus and caudate) are the most affected by motor NSS. | ||
| 650 | 4 | |a Basal ganglia | |
| 650 | 4 | |a Cerebellum | |
| 650 | 4 | |a Motor system | |
| 650 | 4 | |a NSS | |
| 650 | 4 | |a Schizophrenia | |
| 650 | 4 | |a Structural MRI | |
| 650 | 4 | |a Subcortical | |
| 650 | 4 | |a Thalamus | |
| 700 | 1 | |a Herold, Christina |e VerfasserIn |0 (DE-588)1074891791 |0 (DE-627)832651370 |0 (DE-576)285341928 |4 aut | |
| 700 | 1 | |a Kong, Li |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schröder, Johannes |d 1957- |e VerfasserIn |0 (DE-588)138708517 |0 (DE-627)605263469 |0 (DE-576)308769848 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychiatry research. Neuroimaging |d Amsterdam : Elsevier, 1990 |g 300(2020), Artikel-ID 111067, Seite 1-8 |h Online-Ressource |w (DE-627)894201530 |w (DE-600)2900605-3 |w (DE-576)491161778 |x 1872-7506 |7 nnas |a Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis an analysis of NSS motor subscores |
| 773 | 1 | 8 | |g volume:300 |g year:2020 |g elocationid:111067 |g pages:1-8 |g extent:8 |a Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis an analysis of NSS motor subscores |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.pscychresns.2020.111067 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0925492720300391 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200813 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 138708517 |a Schröder, Johannes |m 138708517:Schröder, Johannes |d 910000 |d 910600 |e 910000PS138708517 |e 910600PS138708517 |k 0/910000/ |k 1/910000/910600/ |p 4 |y j | ||
| 998 | |g 1074891791 |a Herold, Christina |m 1074891791:Herold, Christina |d 910000 |d 910600 |e 910000PH1074891791 |e 910600PH1074891791 |k 0/910000/ |k 1/910000/910600/ |p 2 | ||
| 999 | |a KXP-PPN172696888X |e 3739240806 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"31 March 2020","dateIssuedKey":"2020"}],"recId":"172696888X","relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"894201530","origin":[{"dateIssuedDisp":"[1990]-","publisher":"Elsevier","publisherPlace":"Amsterdam"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1872-7506"],"zdb":["2900605-3"],"eki":["894201530"]},"disp":"Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis an analysis of NSS motor subscoresPsychiatry research. Neuroimaging","note":["Gesehen am 24.03.2023"],"title":[{"title_sort":"Psychiatry research","title":"Psychiatry research","partname":"Neuroimaging : the official publication of the International Society for Neuroimaging in Psychiatry"}],"part":{"text":"300(2020), Artikel-ID 111067, Seite 1-8","year":"2020","volume":"300","extent":"8","pages":"1-8"},"language":["eng"],"pubHistory":["Volume 35, issue 1 (1990)-"]}],"note":["Gesehen am 13.08.2020"],"id":{"eki":["172696888X"],"doi":["10.1016/j.pscychresns.2020.111067"]},"physDesc":[{"extent":"8 S."}],"name":{"displayForm":["David Quispe Escudero, Christina J. Herold, Li Kong, Johannes Schröder"]},"person":[{"family":"Quispe Escudero","given":"David","role":"aut","display":"Quispe Escudero, David"},{"family":"Herold","display":"Herold, Christina","role":"aut","given":"Christina"},{"display":"Kong, Li","given":"Li","role":"aut","family":"Kong"},{"family":"Schröder","role":"aut","given":"Johannes","display":"Schröder, Johannes"}],"language":["eng"],"title":[{"subtitle":"an analysis of NSS motor subscores","title":"Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis","title_sort":"Neurological soft signs (NSS) and gray matter volume (GMV) in first-episode psychosis"}]} | ||
| SRT | |a QUISPEESCUNEUROLOGIC3120 | ||