Right ventricular long axis strain: validation of a novel parameter in non-ischemic dilated cardiomyopathy using standard cardiac magnetic resonance imaging
Purpose - Right ventricular longitudinal axis strain (RV-LAS) is a simple measure of RV longitudinal function. The purpose of this study was the evaluation of its diagnostic performance in non-ischemic dilated cardiomyopathy (NIDCM) and the determination of reference values in controls. - Methods -...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 May 2016
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| In: |
European journal of radiology
Year: 2016, Jahrgang: 85, Heft: 7, Pages: 1322-1328 |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2016.04.017 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2016.04.017 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X16301383 
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| Verfasserangaben: | Nisha Arenja, Johannes H. Riffel, Charly Noel Djiokou, Florian Andre, Thomas Fritz, Manuel Halder, Thomas Zelniker, Arnt V. Kristen, Grigorios Korosoglou, Hugo A. Katus, Sebastian J. Buss |
| Zusammenfassung: | Purpose - Right ventricular longitudinal axis strain (RV-LAS) is a simple measure of RV longitudinal function. The purpose of this study was the evaluation of its diagnostic performance in non-ischemic dilated cardiomyopathy (NIDCM) and the determination of reference values in controls. - Methods - 217 NIDCM patients and 200 healthy controls were analysed retrospectively regarding the diagnostic performance of RV-LAS using receiver operating characteristic curves in comparison with RV ejection fraction (RVEF), tricuspid annular plane systolic excursion (TAPSE) and global longitudinal strain (RV-GLS). Hereby, four different approaches were evaluated to assess RV-LAS based on different reference points. RV-LAS LVapex/mid was defined as the change in distance between the LV apex and the middle of a line connecting the origins of the tricuspidal valve leaflets in systole and diastole. The ethical approval was obtained in all participants. - Results - NIDCM and controls were 48 years in mean. Controls were equally gender distributed, while the proportion of men with NIDCM was higher with 77%. Among the four approaches RV-LAS LVapex/mid provided the highest diagnostic performance for discrimination between NIDCM and controls (AUC=0.94). Of all RV functional parameters RV-LAS LVapex/mid preformed significantly better than RVEF (delta AUC=0.05; p=0.003), TAPSE (delta AUC=0.23; p<0.0001) and RV-GLS (delta AUC=0.31; p<0.0001). A significant correlation was found between RV-LAS LVapex/mid and RVEF (r=−0.65; p<0.0001). The reference mean values for RV-LAS LVapex/mid were −17.4±3.5 for men and −18.5±3.7 for women. - Conclusion - RV-LAS showed better diagnostic accuracy for RV dysfunction than RVEF, TAPSE and RV-GLS. Furthermore, it has a rapid accessibility and low intra- and interobserver variability. |
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| Beschreibung: | Gesehen am 18.08.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2016.04.017 |