Alcoholic liver disease: a synopsis of the Charles Lieber's Memorial Symposia 2009-2012
This paper is based upon the ‘Charles Lieber Satellite Symposia’ organized by Manuela G. Neuman at each of the 2009–2012 Research Society on Alcoholism (RSA) Annual Meetings. The presentations represent a broad spectrum dealing with alcoholic liver disease (ALD). In addition, a literature search (20...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 May 2014
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| In: |
Alcohol and alcoholism
Year: 2014, Jahrgang: 49, Heft: 4, Pages: 373-380 |
| ISSN: | 1464-3502 |
| DOI: | 10.1093/alcalc/agu021 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/alcalc/agu021 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/alcalc/article/49/4/373/230634 |
| Verfasserangaben: | Manuela G. Neuman, Lawrence Cohen, Samir Zakhari, Radu M. Nanau, Sebastian Mueller, Michelle Schneider, Charles Parry, Romina Isip and Helmut K. Seitz |
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| 520 | |a This paper is based upon the ‘Charles Lieber Satellite Symposia’ organized by Manuela G. Neuman at each of the 2009–2012 Research Society on Alcoholism (RSA) Annual Meetings. The presentations represent a broad spectrum dealing with alcoholic liver disease (ALD). In addition, a literature search (2008–2013) in the discussed area was performed in order to obtain updated data. The presentations are focused on genetic polymorphisms of ethanol metabolizing enzymes and the role of cytochrome P4502E1 (CYP2E1) in ALD. In addition, alcohol-mediated hepatocarcinogenesis, immune response to alcohol and fibrogenesis in alcoholic hepatitis as well as its co-morbidities with chronic viral hepatitis infections in the presence or absence of human deficiency virus are discussed. Finally, emphasis was led on alcohol and drug interactions as well as liver transplantation for end-stage ALD. | ||
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