Synthesis of functionalized chromones through sequential reactions in aqueous media
An efficient sequential four-component reaction of chromone carbaldehydes, Meldrum's acid, 4-hydroxyl coumarin or 6-methyl-4-hydroxyl-pyrone and primary alcohols is reported which leads to 5a-i in aqueous media. Replacing the primary alcohol with isopropyl alcohol and tert-butyl alcohol results...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 May 2014
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| In: |
Organic & biomolecular chemistry
Year: 2014, Jahrgang: 12, Heft: 30, Pages: 5757-5765 |
| ISSN: | 1477-0539 |
| DOI: | 10.1039/C4OB00618F |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/C4OB00618F Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2014/ob/c4ob00618f 
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| Verfasserangaben: | Saber Mehrparvar, Saeed Balalaie, Mahnaz Rabbanizadeh, Frank Rominger and Elmira Ghabraie |
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| 520 | |a An efficient sequential four-component reaction of chromone carbaldehydes, Meldrum's acid, 4-hydroxyl coumarin or 6-methyl-4-hydroxyl-pyrone and primary alcohols is reported which leads to 5a-i in aqueous media. Replacing the primary alcohol with isopropyl alcohol and tert-butyl alcohol results in different products 10 and 11. The environmentally friendly features, good to high yields and easy work-up are advantages of this approach. | ||
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