The bidirectional tumor: mesenchymal stromal cell interaction promotes the progression of head and neck cancer
Mesenchymal stromal cells (MSC) are an integral cellular component of the tumor microenvironment. Nevertheless, very little is known about MSC originating from human malignant tissue and modulation of these cells by tumor-derived factors. The aim of this study was to isolate and characterize MSC fro...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 August 2014
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| In: |
Stem cell research & therapy
Year: 2014, Jahrgang: 5, Pages: 1-10 |
| ISSN: | 1757-6512 |
| DOI: | 10.1186/scrt484 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/scrt484 Verlag, lizenzpflichtig, Volltext: https://stemcellres.biomedcentral.com/articles/10.1186/scrt484 |
| Verfasserangaben: | Benjamin A. Kansy, Philip A. Dißmann, Hatim Hemeda, Kirsten Bruderek, Anna M. Westerkamp, Vivien Jagalski, Patrick Schuler, Katinka Kansy, Stephan Lang, Claudia A. Dumitru and Sven Brandau |
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| 520 | |a Mesenchymal stromal cells (MSC) are an integral cellular component of the tumor microenvironment. Nevertheless, very little is known about MSC originating from human malignant tissue and modulation of these cells by tumor-derived factors. The aim of this study was to isolate and characterize MSC from head and neck squamous cell carcinoma (HNSCC) and to investigate their interaction with tumor cells. | ||
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