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Coaxiality of Foxb1- and parvalbumin-expressing neurons in the lateral hypothalamic PV1-nucleus

In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region...

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Hauptverfasser: Bilella, Alessandro (VerfasserIn) , Alvarez-Bolado, Gonzalo (VerfasserIn) , Celio, Marco (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 February 2014
In: Neuroscience letters
Year: 2014, Jahrgang: 566, Pages: 111-114
ISSN:1872-7972
DOI:10.1016/j.neulet.2014.02.028
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neulet.2014.02.028
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0304394014001323
Volltext
Verfasserangaben:Alessandro Bilella, Gonzalo Alvarez-Bolado, Marco R. Celio

MARC

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520 |a In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region that is occupied by the PV1-nucleus. They formed a cloud around the axial cord of the parvalbumin-immunopositive cells, which they greatly outnumber (3:1). Only a small proportion of the neurons in the PV1-nucleus co-expressed both parvalbumin and Foxb1. In the light of these findings, a redesignation of this lateral hypothalamic structure as the PV1-Foxb1 nucleus would more accurately reflect its specific biochemical properties. 
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