The impact of hematocrit on oxygenation-sensitive cardiovascular magnetic resonance

Oxygenation-sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a promising utility in the diagnosis of heart disease. Contrast in OS-CMR images is generated through deoxyhemoglobin in the tissue, which is negatively correlated with the signal intensity (SI). Thus, changing hematocrit levels m...

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Hauptverfasser: Günsch, Dominik (VerfasserIn) , Nadeshalingam, Gobinath (VerfasserIn) , Fischer, Kady (VerfasserIn) , Stalder, Aurelien F. (VerfasserIn) , Friedrich, Matthias (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 20 July 2016
In: Journal of cardiovascular magnetic resonance
Year: 2016, Jahrgang: 18, Pages: 1-9
ISSN:1532-429X
DOI:10.1186/s12968-016-0262-1
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12968-016-0262-1
Volltext
Verfasserangaben:Dominik P. Guensch, Gobinath Nadeshalingam, Kady Fischer, Aurelien F. Stalder and Matthias G. Friedrich

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520 |a Oxygenation-sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a promising utility in the diagnosis of heart disease. Contrast in OS-CMR images is generated through deoxyhemoglobin in the tissue, which is negatively correlated with the signal intensity (SI). Thus, changing hematocrit levels may be a confounder in the interpretation of OS-CMR results. We hypothesized that hemodilution confounds the observed signal intensity in OS-CMR images. 
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