Genome-wide association studies in pediatric chronic kidney disease
The genome-wide association study (GWAS) has become an established scientific method that provides an unbiased screen for genetic loci potentially associated with phenotypes of clinical interest such as chronic kidney disease (CKD). Thus, GWAS provides opportunities to gain new perspectives regardin...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
|
| In: |
Pediatric nephrology
Year: 2015, Volume: 31, Issue: 8, Pages: 1241-1252 |
| ISSN: | 1432-198X |
| DOI: | 10.1007/s00467-015-3235-y |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00467-015-3235-y Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287054/ |
| Author Notes: | Jayanta Gupta, Peter A. Kanetsky, Matthias Wuttke, Anna Köttgen, Franz Schaefer, and Craig S. Wong |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1727957563 | ||
| 003 | DE-627 | ||
| 005 | 20241225024055.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200828r20162015xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00467-015-3235-y |2 doi | |
| 035 | |a (DE-627)1727957563 | ||
| 035 | |a (DE-599)KXP1727957563 | ||
| 035 | |a (OCoLC)1341357872 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Gupta, Jayanta |e VerfasserIn |0 (DE-588)1208941534 |0 (DE-627)1696067944 |4 aut | |
| 245 | 1 | 0 | |a Genome-wide association studies in pediatric chronic kidney disease |c Jayanta Gupta, Peter A. Kanetsky, Matthias Wuttke, Anna Köttgen, Franz Schaefer, and Craig S. Wong |
| 264 | 1 | |c 2016 | |
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a 21 October 2015 | ||
| 500 | |a Gesehen am 28.08.2020 | ||
| 520 | |a The genome-wide association study (GWAS) has become an established scientific method that provides an unbiased screen for genetic loci potentially associated with phenotypes of clinical interest such as chronic kidney disease (CKD). Thus, GWAS provides opportunities to gain new perspectives regarding the genetic architecture of CKD progression by identifying new candidate genes and targets for intervention. Thus it has become an important arm of translational science providing a complementary line of investigation to identify novel therapeutics to treat CKD. In this review, we describe the method and the challenges of performing GWAS in the pediatric CKD population. We also provide an overview of successful GWAS for kidney disease, and we discuss the established pediatric CKD cohorts in North America and Europe that are poised to identify genetic risk variants associated with CKD progression. | ||
| 534 | |c 2015 | ||
| 700 | 1 | |a Kanetsky, Peter A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wuttke, Matthias |e VerfasserIn |4 aut | |
| 700 | 1 | |8 1\p |a Köttgen, Anna |d 1974- |e VerfasserIn |0 (DE-588)123510333 |0 (DE-627)706326423 |0 (DE-576)178153028 |4 aut | |
| 700 | 1 | |a Schaefer, Franz |d 1961- |e VerfasserIn |0 (DE-588)1023365383 |0 (DE-627)718365577 |0 (DE-576)366705598 |4 aut | |
| 700 | 1 | |a Wong, Craig S. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Pediatric nephrology |d Berlin : Springer, 1987 |g 31(2016), 8, Seite 1241-1252 |h Online-Ressource |w (DE-627)254638872 |w (DE-600)1463004-7 |w (DE-576)074531689 |x 1432-198X |7 nnas |a Genome-wide association studies in pediatric chronic kidney disease |
| 773 | 1 | 8 | |g volume:31 |g year:2016 |g number:8 |g pages:1241-1252 |g extent:12 |a Genome-wide association studies in pediatric chronic kidney disease |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00467-015-3235-y |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287054/ |x Verlag |z lizenzpflichtig |3 Volltext |
| 883 | |8 1\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 951 | |a AR | ||
| 992 | |a 20200828 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1023365383 |a Schaefer, Franz |m 1023365383:Schaefer, Franz |d 910000 |d 910500 |e 910000PS1023365383 |e 910500PS1023365383 |k 0/910000/ |k 1/910000/910500/ |p 5 | ||
| 999 | |a KXP-PPN1727957563 |e 3743479737 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"display":"Gupta, Jayanta","role":"aut","family":"Gupta","given":"Jayanta"},{"given":"Peter A.","display":"Kanetsky, Peter A.","family":"Kanetsky","role":"aut"},{"display":"Wuttke, Matthias","family":"Wuttke","role":"aut","given":"Matthias"},{"role":"aut","family":"Köttgen","display":"Köttgen, Anna","given":"Anna"},{"display":"Schaefer, Franz","role":"aut","family":"Schaefer","given":"Franz"},{"family":"Wong","role":"aut","display":"Wong, Craig S.","given":"Craig S."}],"language":["eng"],"note":["21 October 2015","Gesehen am 28.08.2020"],"name":{"displayForm":["Jayanta Gupta, Peter A. Kanetsky, Matthias Wuttke, Anna Köttgen, Franz Schaefer, and Craig S. Wong"]},"origin":[{"dateIssuedDisp":"2016","dateIssuedKey":"2016"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1727957563","id":{"eki":["1727957563"],"doi":["10.1007/s00467-015-3235-y"]},"title":[{"title_sort":"Genome-wide association studies in pediatric chronic kidney disease","title":"Genome-wide association studies in pediatric chronic kidney disease"}],"physDesc":[{"extent":"12 S."}],"relHost":[{"pubHistory":["1.1987 -"],"note":["Gesehen am 06.12.05"],"language":["eng"],"disp":"Genome-wide association studies in pediatric chronic kidney diseasePediatric nephrology","origin":[{"publisher":"Springer ; Springer","dateIssuedDisp":"1987-","publisherPlace":"Berlin ; Heidelberg ; Berlin ; Heidelberg ; New York, NY","dateIssuedKey":"1987"}],"recId":"254638872","id":{"zdb":["1463004-7"],"eki":["254638872"],"issn":["1432-198X"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Pediatric nephrology","subtitle":"journal of the International Pediatric Nephrology Association","title":"Pediatric nephrology"}],"part":{"volume":"31","text":"31(2016), 8, Seite 1241-1252","issue":"8","pages":"1241-1252","year":"2016","extent":"12"}}]} | ||
| SRT | |a GUPTAJAYANGENOMEWIDE2016 | ||