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Synthesis of functionalized β-lactams and pyrrolidine-2,5-diones through a metal-free sequential Ugi-4CR/cyclization reaction

An efficient approach for the synthesis of functionalized β-lactams and pyrrolidine-2,5-diones was achieved through a sequential Ugi-4CR/cyclization reaction. Diversity-oriented synthesis, good to high yields, easy workup, and short reaction times are advantages of this procedure.

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Bibliographic Details
Main Authors: Ghabraie, Elmira (Author) , Balalaie, Saeed (Author) , Mehrparvar, Saber (Author) , Rominger, Frank (Author)
Format: Article (Journal)
Language:English
Published: [2014]
In: The journal of organic chemistry
Year: 2014, Volume: 79, Issue: 17, Pages: 7926-7934
ISSN:1520-6904
DOI:10.1021/jo5010422
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/jo5010422
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Author Notes:Elmira Ghabraie, Saeed Balalaie, Saber Mehrparvar, and Frank Rominger
Description
Summary:An efficient approach for the synthesis of functionalized β-lactams and pyrrolidine-2,5-diones was achieved through a sequential Ugi-4CR/cyclization reaction. Diversity-oriented synthesis, good to high yields, easy workup, and short reaction times are advantages of this procedure.
Item Description:Gesehen am 03.09.2020
Physical Description:Online Resource
ISSN:1520-6904
DOI:10.1021/jo5010422

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