Fecal DNA methylation markers for detecting stages of colorectal cancer and its precursors: a systematic review

DNA methylation biomarkers in stool may have applications in early colorectal cancer (CRC) detection; however, their association with stages of CRC carcinogenesis or their performance in detecting various stages is unclear. We aimed to systematically review the evidence for DNA methylation markers i...

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Hauptverfasser: Raut, Janhavi R. (VerfasserIn) , Guan, Zhong (VerfasserIn) , Schrotz-King, Petra (VerfasserIn) , Brenner, Hermann (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 10 August 2020
In: Clinical epigenetics
Year: 2020, Jahrgang: 12, Heft: 1
ISSN:1868-7083
DOI:10.1186/s13148-020-00904-7
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13148-020-00904-7
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Verfasserangaben:Janhavi R. Raut, Zhong Guan, Petra Schrotz-King and Hermann Brenner
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Zusammenfassung:DNA methylation biomarkers in stool may have applications in early colorectal cancer (CRC) detection; however, their association with stages of CRC carcinogenesis or their performance in detecting various stages is unclear. We aimed to systematically review the evidence for DNA methylation markers in stool for risk stratification or detection of specific CRC stages, as well as precursors of CRC.
Beschreibung:Gesehen am 14.09.2020
Beschreibung:Online Resource
ISSN:1868-7083
DOI:10.1186/s13148-020-00904-7