Spike wave location and density disturb sleep slow waves in patients with CSWS (continuous spike waves during sleep)
In CSWS (continuous spike waves during sleep) activation of spike waves during slow wave sleep has been causally linked to neuropsychological deficits, but the pathophysiologic mechanisms are still unknown. In healthy subjects, the overnight decrease of the slope of slow waves in NREM (non-rapid eye...
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| Main Authors: | , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 20, 2014
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| In: |
Epilepsia
Year: 2014, Volume: 55, Issue: 4, Pages: 584-591 |
| ISSN: | 1528-1167 |
| DOI: | 10.1111/epi.12576 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1111/epi.12576 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.12576 
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| Author Notes: | Bigna K. Bölsterli Heinzle, Sara Fattinger, Salomé Kurth, Monique K. LeBourgeois, Maya Ringli, Thomas Bast, Hanne Critelli, Bernhard Schmitt, and Reto Huber |
| Summary: | In CSWS (continuous spike waves during sleep) activation of spike waves during slow wave sleep has been causally linked to neuropsychological deficits, but the pathophysiologic mechanisms are still unknown. In healthy subjects, the overnight decrease of the slope of slow waves in NREM (non-rapid eye movement) sleep has been linked to brain recovery to regain optimal cognitive performance. Here, we investigated whether the electrophysiologic hallmark of CSWS, the spike waves during sleep, is related to an alteration in the overnight decrease of the slope, and if this alteration is linked to location and density of spike waves. summarizing this article is available for download in the Supporting Information section here. |
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| Item Description: | Gesehen am 16.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1528-1167 |
| DOI: | 10.1111/epi.12576 |