Inhibition of IGF-I-related intracellular signaling pathways by proinflammatory cytokines in growth plate chondrocytes
Children with chronic inflammatory diseases suffer from severe growth failure associated with resistance toward the anabolic action of insulin-like growth factor I (IGF-I). We hypothesized that proinflammatory cytokines interfere with IGF-I signaling.
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
[September 2014]
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| In: |
Pediatric research
Year: 2014, Jahrgang: 76, Heft: 3, Pages: 245-251 |
| ISSN: | 1530-0447 |
| DOI: | 10.1038/pr.2014.84 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/pr.2014.84 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/pr201484 
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| Verfasserangaben: | Daniela Choukair, Ulrike Hügel, Anja Sander, Lorenz Uhlmann and Burkhard Tönshoff |
MARC
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| 520 | |a Children with chronic inflammatory diseases suffer from severe growth failure associated with resistance toward the anabolic action of insulin-like growth factor I (IGF-I). We hypothesized that proinflammatory cytokines interfere with IGF-I signaling. | ||
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