Cover Image

GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ

The granulocyte-macrophage colony-stimulating factor (GM-CSF) (or CSF-2) is involved in myeloid cell growth and differentiation, and, possibly, a major mediator of inflammation in body tissues. The role of GM-CSF in the activation of microglia (CNS resident macrophages) and the consequent impacts on...

Full description

Saved in:
Bibliographic Details
Main Authors: Dikmen, Hasan Onur (Author) , Hemmerich, Marc (Author) , Lewen, Andrea (Author) , Hollnagel, Jan-Oliver (Author) , Chausse de Freitas, Bruno (Author) , Kann, Oliver (Author)
Format: Article (Journal)
Language:English
Published: [2020]
In: Journal of neuroinflammation
Year: 2020, Volume: 17
ISSN:1742-2094
DOI:10.1186/s12974-020-01903-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12974-020-01903-4
Get full text
Author Notes:Hasan Onur Dikmen, Marc Hemmerich, Andrea Lewen, Jan-Oliver Hollnagel, Bruno Chausse and Oliver Kann

MARC

LEADER 00000caa a2200000 c 4500
001 173333260X
003 DE-627
005 20240725143736.0
007 cr uuu---uuuuu
008 200918s2020 xx |||||o 00| ||eng c
024 7 |a 10.1186/s12974-020-01903-4  |2 doi 
035 |a (DE-627)173333260X 
035 |a (DE-599)KXP173333260X 
035 |a (OCoLC)1341360919 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Dikmen, Hasan Onur  |d 1994-  |e VerfasserIn  |0 (DE-588)1187530492  |0 (DE-627)1666548502  |4 aut 
245 1 0 |a GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ  |c Hasan Onur Dikmen, Marc Hemmerich, Andrea Lewen, Jan-Oliver Hollnagel, Bruno Chausse and Oliver Kann 
264 1 |c [2020] 
300 |b Illustrationen 
300 |a 13 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Published: 11 August 2020 
500 |a Gesehen am 18.09.2020 
520 |a The granulocyte-macrophage colony-stimulating factor (GM-CSF) (or CSF-2) is involved in myeloid cell growth and differentiation, and, possibly, a major mediator of inflammation in body tissues. The role of GM-CSF in the activation of microglia (CNS resident macrophages) and the consequent impacts on neuronal survival, excitability, and synaptic transmission are widely unknown, however. Here, we focused on electrical neuronal network rhythms in the gamma frequency band (30-70 Hz). Gamma oscillations are fundamental to higher brain functions, such as perception, attention, and memory, and they are exquisitely sensitive to metabolic and oxidative stress. 
700 1 |a Hemmerich, Marc  |d 1993-  |e VerfasserIn  |0 (DE-588)1260479986  |0 (DE-627)180730910X  |4 aut 
700 1 |a Lewen, Andrea  |e VerfasserIn  |0 (DE-588)1181730813  |0 (DE-627)166236427X  |4 aut 
700 1 |a Hollnagel, Jan-Oliver  |d 1979-  |e VerfasserIn  |0 (DE-588)1126460699  |0 (DE-627)880931965  |0 (DE-576)484503952  |4 aut 
700 1 |a Chausse de Freitas, Bruno  |e VerfasserIn  |0 (DE-588)1187530573  |0 (DE-627)1666549037  |4 aut 
700 1 |a Kann, Oliver  |d 1971-  |e VerfasserIn  |0 (DE-588)123125812  |0 (DE-627)70617223X  |0 (DE-576)293567255  |4 aut 
773 0 8 |i Enthalten in  |t Journal of neuroinflammation  |d London : BioMed Central, 2004  |g 17(2020) Artikel-Nummer 235, 13 Seiten  |h Online-Ressource  |w (DE-627)391784781  |w (DE-600)2156455-3  |w (DE-576)12192985X  |x 1742-2094  |7 nnas  |a GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ 
773 1 8 |g volume:17  |g year:2020  |g extent:13  |a GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ 
856 4 0 |u https://doi.org/10.1186/s12974-020-01903-4  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20200918 
993 |a Article 
994 |a 2020 
998 |g 123125812  |a Kann, Oliver  |m 123125812:Kann, Oliver  |d 50000  |d 53200  |e 50000PK123125812  |e 53200PK123125812  |k 0/50000/  |k 1/50000/53200/  |p 6  |y j 
998 |g 1187530573  |a Chausse de Freitas, Bruno  |m 1187530573:Chausse de Freitas, Bruno  |d 50000  |d 53200  |e 50000PC1187530573  |e 53200PC1187530573  |k 0/50000/  |k 1/50000/53200/  |p 5 
998 |g 1126460699  |a Hollnagel, Jan-Oliver  |m 1126460699:Hollnagel, Jan-Oliver  |p 4 
998 |g 1181730813  |a Lewen, Andrea  |m 1181730813:Lewen, Andrea  |d 50000  |d 53200  |e 50000PL1181730813  |e 53200PL1181730813  |k 0/50000/  |k 1/50000/53200/  |p 3 
998 |g 1260479986  |a Hemmerich, Marc  |m 1260479986:Hemmerich, Marc  |d 50000  |e 50000PH1260479986  |k 0/50000/  |p 2 
999 |a KXP-PPN173333260X  |e 3758615801 
BIB |a Y 
SER |a journal 
JSO |a {"person":[{"family":"Dikmen","given":"Hasan Onur","roleDisplay":"VerfasserIn","display":"Dikmen, Hasan Onur","role":"aut"},{"family":"Hemmerich","given":"Marc","roleDisplay":"VerfasserIn","display":"Hemmerich, Marc","role":"aut"},{"role":"aut","display":"Lewen, Andrea","roleDisplay":"VerfasserIn","given":"Andrea","family":"Lewen"},{"display":"Hollnagel, Jan-Oliver","roleDisplay":"VerfasserIn","role":"aut","family":"Hollnagel","given":"Jan-Oliver"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Chausse de Freitas, Bruno","given":"Bruno","family":"Chausse de Freitas"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Kann, Oliver","given":"Oliver","family":"Kann"}],"title":[{"title":"GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ","title_sort":"GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ"}],"language":["eng"],"recId":"173333260X","note":["Published: 11 August 2020","Gesehen am 18.09.2020"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"name":{"displayForm":["Hasan Onur Dikmen, Marc Hemmerich, Andrea Lewen, Jan-Oliver Hollnagel, Bruno Chausse and Oliver Kann"]},"id":{"doi":["10.1186/s12974-020-01903-4"],"eki":["173333260X"]},"origin":[{"dateIssuedDisp":"[2020]","dateIssuedKey":"2020"}],"relHost":[{"recId":"391784781","language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situJournal of neuroinflammation","note":["Gesehen am 12.07.10"],"part":{"volume":"17","text":"17(2020) Artikel-Nummer 235, 13 Seiten","extent":"13","year":"2020"},"titleAlt":[{"title":"JNI"}],"pubHistory":["1.2004 -"],"title":[{"title":"Journal of neuroinflammation","subtitle":"JNI","title_sort":"Journal of neuroinflammation"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["391784781"],"zdb":["2156455-3"],"issn":["1742-2094"]},"origin":[{"publisherPlace":"London","dateIssuedDisp":"2004-","publisher":"BioMed Central","dateIssuedKey":"2004"}]}],"physDesc":[{"extent":"13 S.","noteIll":"Illustrationen"}]} 
SRT |a DIKMENHASAGMCSFINDUC2020 

Similar Items