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A photoactivatable nanopatterned substrate for analyzing collective cell migration with precisely tuned cell-extracellular matrix ligand interactions

Collective cell migration is involved in many biological and pathological processes. Various factors have been shown to regulate the decision to migrate collectively or individually, but the impact of cell-extracellular matrix (ECM) interactions is still debated. Here, we developed a method for anal...

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Hauptverfasser: Shimizu, Yoshihisa (VerfasserIn) , Böhm, Heike (VerfasserIn) , Yamaguchi, Kazuo (VerfasserIn) , Spatz, Joachim P. (VerfasserIn) , Nakanishi, Jun (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 14, 2014
In: PLOS ONE
Year: 2014, Jahrgang: 9, Heft: 3
ISSN:1932-6203
DOI:10.1371/journal.pone.0091875
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1371/journal.pone.0091875
Verlag, lizenzpflichtig, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091875
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Verfasserangaben:Yoshihisa Shimizu, Heike Boehm, Kazuo Yamaguchi, Joachim P. Spatz, Jun Nakanishi
Beschreibung
Zusammenfassung:Collective cell migration is involved in many biological and pathological processes. Various factors have been shown to regulate the decision to migrate collectively or individually, but the impact of cell-extracellular matrix (ECM) interactions is still debated. Here, we developed a method for analyzing collective cell migration by precisely tuning the interactions between cells and ECM ligands.
Beschreibung:Gesehen am 23.09.2020
Beschreibung:Online Resource
ISSN:1932-6203
DOI:10.1371/journal.pone.0091875

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