Signal peptide peptidase-type proteases: versatile regulators with functions ranging from limited proteolysis to protein degradation

Intramembrane proteases catalyze the unusual cleavage of peptide bonds in the plane of biological membranes. They are categorized according to their active site. The GxGD aspartyl proteases comprise presenilin, the signal peptide peptidase (SPP), and SPP-like (SPPL) proteases. Here we focus on the f...

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Main Authors: Lipp, Sara Suna (Author) , Lemberg, Marius (Author)
Format: Article (Journal)
Language:English
Published: 26 May 2020
In: Journal of molecular biology
Year: 2020, Volume: 432, Issue: 18, Pages: 5063-5078
ISSN:1089-8638
DOI:10.1016/j.jmb.2020.05.014
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jmb.2020.05.014
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0022283620303557
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Author Notes:Sara Suna Yücel and Marius K. Lemberg

MARC

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