Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases
The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a lack of clinico-epidemiological data related to net...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 19, 2014
|
| In: |
PLOS ONE
Year: 2014, Volume: 9, Issue: 3 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0092311 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1371/journal.pone.0092311 Verlag, lizenzpflichtig, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092311 
|
| Author Notes: | Patrick N. Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M. Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P. Steinbach, Karl H. Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1733722564 | ||
| 003 | DE-627 | ||
| 005 | 20241227002731.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200925s2014 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0092311 |2 doi | |
| 035 | |a (DE-627)1733722564 | ||
| 035 | |a (DE-599)KXP1733722564 | ||
| 035 | |a (OCoLC)1341361773 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Harter, Patrick Nikolaus |d 1980- |e VerfasserIn |0 (DE-588)136226558 |0 (DE-627)578113074 |0 (DE-576)300907435 |4 aut | |
| 245 | 1 | 0 | |a Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases |c Patrick N. Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M. Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P. Steinbach, Karl H. Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn |
| 264 | 1 | |c March 19, 2014 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 25.09.2020 | ||
| 520 | |a The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a lack of clinico-epidemiological data related to netrin-1 expression. Therefore, the aim of our study was to elucidate the association of netrin-1 expression and patient survival in brain metastases since those constitute one of the most limiting factors for patient prognosis. | ||
| 650 | 4 | |a Brain metastasis | |
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Colorectal cancer | |
| 650 | 4 | |a Edema | |
| 650 | 4 | |a In situ hybridization | |
| 650 | 4 | |a Non-small cell lung cancer | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Renal cancer | |
| 700 | 1 | |a Zinke, Jenny |d 1982- |e VerfasserIn |0 (DE-588)1079565051 |0 (DE-627)841236941 |0 (DE-576)452801001 |4 aut | |
| 700 | 1 | |8 1\p |a Scholz, Alexander |d 1982- |e VerfasserIn |0 (DE-588)1021834564 |0 (DE-627)715834711 |0 (DE-576)364297581 |4 aut | |
| 700 | 1 | |a Tichy, Julia Frederike |d 1982- |e VerfasserIn |0 (DE-588)142496626 |0 (DE-627)636711129 |0 (DE-576)331044633 |4 aut | |
| 700 | 1 | |a Zachskorn, Cornelia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kvasnicka, Hans M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Goeppert, Benjamin |d 1977- |e VerfasserIn |0 (DE-588)1022581635 |0 (DE-627)717004244 |0 (DE-576)365641324 |4 aut | |
| 700 | 1 | |a Delloye-Bourgeois, Céline |e VerfasserIn |4 aut | |
| 700 | 1 | |8 2\p |a Hattingen, Elke |e VerfasserIn |0 (DE-588)142162485 |0 (DE-627)634415751 |0 (DE-576)328208876 |4 aut | |
| 700 | 1 | |a Senft, Christian |d 1976- |e VerfasserIn |0 (DE-588)131436082 |0 (DE-627)50906051X |0 (DE-576)298476754 |4 aut | |
| 700 | 1 | |8 3\p |a Steinbach, Joachim Peter |d 1966- |e VerfasserIn |0 (DE-588)113564813 |0 (DE-627)523317921 |0 (DE-576)289766818 |4 aut | |
| 700 | 1 | |a Plate, Karl |e VerfasserIn |0 (DE-588)1218305738 |0 (DE-627)1733724796 |4 aut | |
| 700 | 1 | |a Mehlen, Patrick |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schulte, Dorothea |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mittelbronn, Michel Guy André |d 1973- |e VerfasserIn |0 (DE-588)124293654 |0 (DE-627)085766461 |0 (DE-576)185933181 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PLOS ONE |d San Francisco, California, US : PLOS, 2006 |g 9(2014,3) Artikel-Nummer e92311, 10 Seiten |h Online-Ressource |w (DE-627)523574592 |w (DE-600)2267670-3 |w (DE-576)281331979 |x 1932-6203 |7 nnas |a Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases |
| 773 | 1 | 8 | |g volume:9 |g year:2014 |g number:3 |a Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases |
| 856 | 4 | 0 | |u https://doi.org/10.1371/journal.pone.0092311 |x Resolving-System |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092311 |x Verlag |z lizenzpflichtig |3 Volltext |
| 883 | |8 1\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 2\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 3\p |a cgwrk |d 20241001 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 951 | |a AR | ||
| 992 | |a 20200925 | ||
| 993 | |a Article | ||
| 994 | |a 2014 | ||
| 998 | |g 1218305738 |a Plate, Karl |m 1218305738:Plate, Karl |p 12 | ||
| 998 | |g 1022581635 |a Goeppert, Benjamin |m 1022581635:Goeppert, Benjamin |d 910000 |d 912000 |e 910000PG1022581635 |e 912000PG1022581635 |k 0/910000/ |k 1/910000/912000/ |p 7 | ||
| 999 | |a KXP-PPN1733722564 |e 3761064802 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"523574592","name":{"displayForm":["Public Library of Science"]},"language":["eng"],"part":{"year":"2014","text":"9(2014,3) Artikel-Nummer e92311, 10 Seiten","volume":"9","issue":"3"},"physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["523574592"],"zdb":["2267670-3"],"issn":["1932-6203"]},"corporate":[{"display":"Public Library of Science","role":"isb"}],"origin":[{"publisher":"PLOS ; PLoS","dateIssuedDisp":"2006-","publisherPlace":"San Francisco, California, US ; Lawrence, Kan.","dateIssuedKey":"2006"}],"disp":"Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastasesPLOS ONE","note":["Schreibweise des Titels bis 2012: PLoS ONE","Gesehen am 20.03.19"],"pubHistory":["1.2006 -"],"title":[{"title_sort":"PLOS ONE","title":"PLOS ONE"}]}],"title":[{"title_sort":"Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases","title":"Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"doi":["10.1371/journal.pone.0092311"],"eki":["1733722564"]},"recId":"1733722564","name":{"displayForm":["Patrick N. Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M. Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P. Steinbach, Karl H. Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn"]},"origin":[{"dateIssuedDisp":"March 19, 2014","dateIssuedKey":"2014"}],"language":["eng"],"note":["Gesehen am 25.09.2020"],"person":[{"given":"Patrick Nikolaus","role":"aut","family":"Harter","display":"Harter, Patrick Nikolaus"},{"display":"Zinke, Jenny","role":"aut","family":"Zinke","given":"Jenny"},{"role":"aut","family":"Scholz","display":"Scholz, Alexander","given":"Alexander"},{"role":"aut","family":"Tichy","display":"Tichy, Julia Frederike","given":"Julia Frederike"},{"role":"aut","family":"Zachskorn","display":"Zachskorn, Cornelia","given":"Cornelia"},{"given":"Hans M.","role":"aut","family":"Kvasnicka","display":"Kvasnicka, Hans M."},{"given":"Benjamin","display":"Goeppert, Benjamin","role":"aut","family":"Goeppert"},{"role":"aut","family":"Delloye-Bourgeois","display":"Delloye-Bourgeois, Céline","given":"Céline"},{"role":"aut","family":"Hattingen","display":"Hattingen, Elke","given":"Elke"},{"family":"Senft","role":"aut","display":"Senft, Christian","given":"Christian"},{"family":"Steinbach","role":"aut","display":"Steinbach, Joachim Peter","given":"Joachim Peter"},{"given":"Karl","role":"aut","family":"Plate","display":"Plate, Karl"},{"given":"Patrick","display":"Mehlen, Patrick","family":"Mehlen","role":"aut"},{"display":"Schulte, Dorothea","family":"Schulte","role":"aut","given":"Dorothea"},{"family":"Mittelbronn","role":"aut","display":"Mittelbronn, Michel Guy André","given":"Michel Guy André"}]} | ||
| SRT | |a HARTERPATRNETRIN1EXP1920 | ||