Using immunotherapy to boost the abscopal effect

The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts and limitations of using a combination of radiotherapy and immunotherapy to boost the abscop...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ngwa, Wilfred (VerfasserIn) , Hesser, Jürgen (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: May 2018
In: Nature reviews. Cancer
Year: 2018, Jahrgang: 18, Heft: 5, Pages: 313-322
ISSN:1474-1768
DOI:10.1038/nrc.2018.6
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nrc.2018.6
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nrc.2018.6
Volltext
Verfasserangaben:Wilfred Ngwa, Omoruyi Credit Irabor, Jonathan D. Schoenfeld, Jürgen Hesser, Sandra Demaria and Silvia C. Formenti
Beschreibung
Zusammenfassung:The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts and limitations of using a combination of radiotherapy and immunotherapy to boost the abscopal effect.
Beschreibung:Gesehen am 29.09.2020
Beschreibung:Online Resource
ISSN:1474-1768
DOI:10.1038/nrc.2018.6