Genetic variants in the glutathione S-transferase genes and survival in colorectal cancer patients after chemotherapy and differences according to treatment with oxaliplatin
Introduction: The glutathione S-transferase (GST) enzymes are involved in the detoxification of a range of carcinogenic compounds as well as chemotherapeutic agents. Therefore, genetic variants in the GST genes could influence survival in patients with colorectal cancer (CRC). Results from previous...
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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 2014
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| In: |
Pharmacogenetics and genomics
Year: 2014, Volume: 24, Issue: 7, Pages: 340-347 |
| ISSN: | 1744-6880 |
| DOI: | 10.1097/FPC.0000000000000059 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/FPC.0000000000000059 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/jpharmacogenetics/Fulltext/2014/07000/Genetic_variants_in_the_glutathione_S_transferase.2.aspx |
| Author Notes: | Elisabeth J. Kap, Swantje Richter, Anja Rudolph, Lina Jansen, Alexis Ulrich, Michael Hoffmeister, Cornelia M. Ulrich, Hermann Brenner and Jenny Chang-Claude |