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A systematic review of global alpha-tocopherol status as assessed by nutritional intake levels and blood serum concentrations

The purpose of this study is to systematically review the published literature reporting vitamin E intake levels and serum concentrations in order to obtain a global overview of α-tocopherol status. Articles published between 2000 and 2012 were considered; 176 articles referring to 132 single studie...

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Main Authors: Péter, Szabolcs (Author) , Friedel, Angelika (Author) , Roos, Franz F. (Author) , Wyss, Adrian (Author) , Eggersdorfer, Manfred (Author) , Hoffmann, Kristina (Author) , Weber, Peter (Author)
Format: Article (Journal)
Language:English
Published: Juni 14, 2016
In: International journal for vitamin and nutrition research
Year: 2015, Volume: 85, Issue: 5-6, Pages: 261-281
ISSN:1664-2821
DOI:10.1024/0300-9831/a000281
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1024/0300-9831/a000281
Verlag, lizenzpflichtig, Volltext: https://econtent.hogrefe.com/doi/10.1024/0300-9831/a000281
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Author Notes:Szabolcs Péter, Angelika Friedel, Franz F. Roos, Adrian Wyss, Manfred Eggersdorfer, Kristina Hoffmann, and Peter Weber
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Summary:The purpose of this study is to systematically review the published literature reporting vitamin E intake levels and serum concentrations in order to obtain a global overview of α-tocopherol status. Articles published between 2000 and 2012 were considered; 176 articles referring to 132 single studies were included. Applying an RDA (recommended daily allowance) of 15 mg/day and EAR (estimated average requirement) of 12 mg/day to all populations with a minimum age of 14 years, 82 and 61 % of mean and median data points were below the RDA and the EAR, respectively. Regarding serum concentrations, globally 13 % of the included data points were below the functional deficiency threshold concentration of 12 μmol/L, mostly for newborns and children. Several prospective observational studies suggest that a serum α-tocopherol concentration of ≥30 μmol/L has beneficial effects on human health. Of the reported study populations and subpopulations, only 21 % reached this threshold globally. This systematic review suggests that the α-tocopherol status is inadequate in a substantial part of the studied populations.
Item Description:Gesehen am 07.10.2020
Physical Description:Online Resource
ISSN:1664-2821
DOI:10.1024/0300-9831/a000281

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