Mitochondria tether protein trash to rejuvenate cellular environments
Protein damage segregates asymmetrically in dividing yeast cells, rejuvenating daughters at the expense of mother cells. Zhou et al. now show that newly synthesized proteins are particularly prone to aggregation and describe a mechanism that tethers aggregated proteins to mitochondria. This associat...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 October 2014
|
| In: |
Cell
Year: 2014, Volume: 159, Issue: 3, Pages: 471-472 |
| ISSN: | 1097-4172 |
| DOI: | 10.1016/j.cell.2014.10.007 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.cell.2014.10.007 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S009286741401294X 
|
| Author Notes: | Axel Mogk, Bernd Bukau |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1735246883 | ||
| 003 | DE-627 | ||
| 005 | 20240407193334.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201009s2014 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.cell.2014.10.007 |2 doi | |
| 035 | |a (DE-627)1735246883 | ||
| 035 | |a (DE-599)KXP1735246883 | ||
| 035 | |a (OCoLC)1341370944 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Mogk, Axel |e VerfasserIn |0 (DE-588)102799914X |0 (DE-627)73031166X |0 (DE-576)180449338 |4 aut | |
| 245 | 1 | 0 | |a Mitochondria tether protein trash to rejuvenate cellular environments |c Axel Mogk, Bernd Bukau |
| 264 | 1 | |c 23 October 2014 | |
| 300 | |a 2 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 09.10.2020 | ||
| 520 | |a Protein damage segregates asymmetrically in dividing yeast cells, rejuvenating daughters at the expense of mother cells. Zhou et al. now show that newly synthesized proteins are particularly prone to aggregation and describe a mechanism that tethers aggregated proteins to mitochondria. This association constrains aggregate mobility, effectively retaining and sorting toxic aggregates away from younger cells. | ||
| 700 | 1 | |a Bukau, Bernd |d 1954- |e VerfasserIn |0 (DE-588)143209019 |0 (DE-627)643892575 |0 (DE-576)335649270 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cell |d [Cambridge, Mass.] : Cell Press, 1974 |g 159(2014), 3, Seite 471-472 |h Online-Ressource |w (DE-627)320416127 |w (DE-600)2001951-8 |w (DE-576)090881370 |x 1097-4172 |7 nnas |a Mitochondria tether protein trash to rejuvenate cellular environments |
| 773 | 1 | 8 | |g volume:159 |g year:2014 |g number:3 |g pages:471-472 |g extent:2 |a Mitochondria tether protein trash to rejuvenate cellular environments |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.cell.2014.10.007 |x Resolving-System |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S009286741401294X |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20201009 | ||
| 993 | |a Article | ||
| 994 | |a 2014 | ||
| 998 | |g 143209019 |a Bukau, Bernd |m 143209019:Bukau, Bernd |d 700000 |d 706000 |e 700000PB143209019 |e 706000PB143209019 |k 0/700000/ |k 1/700000/706000/ |p 2 |y j | ||
| 998 | |g 102799914X |a Mogk, Axel |m 102799914X:Mogk, Axel |d 700000 |d 706000 |e 700000PM102799914X |e 706000PM102799914X |k 0/700000/ |k 1/700000/706000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1735246883 |e 3773909322 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"2 S."}],"note":["Gesehen am 09.10.2020"],"relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"origin":[{"dateIssuedDisp":"1974-","publisherPlace":"[Cambridge, Mass.] ; New York, NY","publisher":"Cell Press ; Elsevier","dateIssuedKey":"1974"}],"pubHistory":["1.1974 -"],"language":["eng"],"title":[{"title_sort":"Cell","title":"Cell"}],"part":{"text":"159(2014), 3, Seite 471-472","volume":"159","issue":"3","pages":"471-472","year":"2014","extent":"2"},"id":{"zdb":["2001951-8"],"issn":["1097-4172"],"eki":["320416127"]},"recId":"320416127","disp":"Mitochondria tether protein trash to rejuvenate cellular environmentsCell","physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 11.03.24"]}],"id":{"doi":["10.1016/j.cell.2014.10.007"],"eki":["1735246883"]},"recId":"1735246883","title":[{"title_sort":"Mitochondria tether protein trash to rejuvenate cellular environments","title":"Mitochondria tether protein trash to rejuvenate cellular environments"}],"person":[{"family":"Mogk","given":"Axel","role":"aut","display":"Mogk, Axel"},{"display":"Bukau, Bernd","given":"Bernd","role":"aut","family":"Bukau"}],"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"name":{"displayForm":["Axel Mogk, Bernd Bukau"]},"origin":[{"dateIssuedKey":"2014","dateIssuedDisp":"23 October 2014"}]} | ||
| SRT | |a MOGKAXELBUMITOCHONDR2320 | ||