A system for three-dimensional dosimetric verification of treatment plans in intensity-modulated radiotherapy with heavy ions

The introduction of dynamic intensity modulation into radiotherapy using conventional photon beams or scanning particle beams requires additional and efficient methods of dose verification. Dose measurements in dynamically generated dose distributions with a single ionization chamber require a compl...

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Hauptverfasser: Karger, Christian (VerfasserIn) , Jäkel, Oliver (VerfasserIn) , Hartmann, Günther H. (VerfasserIn) , Heeg, Peter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 01 October 1999
In: Medical physics
Year: 1999, Jahrgang: 26, Heft: 10, Pages: 2125-2132
ISSN:2473-4209
DOI:10.1118/1.598728
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1118/1.598728
Verlag, lizenzpflichtig, Volltext: https://aapm.onlinelibrary.wiley.com/doi/abs/10.1118/1.598728
Volltext
Verfasserangaben:Christian P. Karger, Oliver Jäkel, and Günther H. Hartmann, Deutsches Krebsforschungszentrum, Abteilung Medizinische Physik, Peter Heeg, Radiologische Klinik der Universität Heidelberg

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520 |a The introduction of dynamic intensity modulation into radiotherapy using conventional photon beams or scanning particle beams requires additional and efficient methods of dose verification. Dose measurements in dynamically generated dose distributions with a single ionization chamber require a complete application of the treatment field for each single measurement. Therefore measurements are performed by simultaneous use of multiple ionization chambers. The measurement is performed by a computer controlled system and is comprised of the following steps: (a) automated positioning of the ionization chambers, (b) measurement at these points, (c) a comparison with the calculated dose from the treatment planning system, and (d) documentation of the measurement. The ionization chambers are read out by a multichannel electrometer and are densely packed into a mounting of polymethylmetacrylate, which is attached to the arm of a three-dimensional motor- driven water phantom. The measured and planned dose values are displayed numerically as well as graphically. The mean deviation between measured and planned doses as well as their standard deviation are calculated and displayed. Through printouts complete documentation of the measurement is obtained and a quick decision can be made whether the dose distribution is acceptable for the patient. The system is now routinely used for dose verification at the heavy ion therapy project at the Gesellschaft für Schwerionenforschung in Darmstadt. Up to now 242 measurements have been performed for heavy ion treatment of 30 patients. The system allows efficient verification and documentation of carbon ion fields and is in principle also applicable to intensity-modulated photon beams. 
650 4 |a and avalanche counters 
650 4 |a beam intensity 
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650 4 |a Dosimetry 
650 4 |a Dosimetry/exposure assessment 
650 4 |a Gas-filled counters: ionization chambers 
650 4 |a Heavy ion beams 
650 4 |a Intense charged particle beams 
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650 4 |a Particle beam dynamics 
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650 4 |a Particle beam profile 
650 4 |a Particle beams 
650 4 |a Photons 
650 4 |a Positive-ion beams 
650 4 |a proportional 
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650 4 |a Radiation therapy 
650 4 |a Treatment strategy 
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