Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers

Modulation of immunologic interactions in cancer tissue is a promising therapeutic strategy. To investigate the immunogenicity of human epidermal growth factor receptor 2 (HER2) -positive and triple-negative (TN) breast cancers (BCs), we evaluated tumor-infiltrating lymphocytes (TILs) and immunologi...

Full description

Bibliographic Details

Main Authors:	Denkert, Carsten (Author) , Minckwitz, Gunter von (Author) , Brase, Jan Christoph (Author) , Sinn, Bruno V. (Author) , Gade, Stephan (Author) , Kronenwett, Ralf (Author) , Pfitzner, Berit M. (Author) , Salat, Christoph (Author) , Loi, Sherene (Author) , Schmitt, Wolfgang D. (Author) , Schem, Christian (Author) , Fisch, Karin (Author) , Darb-Esfahani, Silvia (Author) , Mehta, Keyur (Author) , Sotiriou, Christos (Author) , Wienert, Stephan (Author) , Klare, Peter (Author) , André, Fabrice (Author) , Klauschen, Frederick (Author) , Blohmer, Jens-Uwe (Author) , Krappmann, Kristin (Author) , Schmidt, Marcus (Author) , Tesch, Hans (Author) , Kümmel, Sherko (Author) , Sinn, Peter (Author) , Jackisch, Christian (Author) , Dietel, Manfred (Author) , Reimer, Toralf (Author) , Untch, Michael (Author) , Loibl, Sibylle (Author)
Format:	Article (Journal)
Language:	English
Published:	2015
In:	Journal of clinical oncology Year: 2014, Volume: 33, Issue: 9, Pages: 983-991
ISSN:	1527-7755
DOI:	10.1200/JCO.2014.58.1967
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1200/JCO.2014.58.1967 Verlag, lizenzpflichtig, Volltext: https://ascopubs.org/doi/10.1200/JCO.2014.58.1967
Author Notes:	Carsten Denkert, Gunter von Minckwitz, Jan C. Brase, Bruno V. Sinn, Stephan Gade, Ralf Kronenwett, Berit M. Pfitzner, Christoph Salat, Sherene Loi, Wolfgang D. Schmitt, Christian Schem, Karin Fisch, Silvia Darb-Esfahani, Keyur Mehta, Christos Sotiriou, Stephan Wienert, Peter Klare, Fabrice André, Frederick Klauschen, Jens-Uwe Blohmer, Kristin Krappmann, Marcus Schmidt, Hans Tesch, Sherko Kümmel, Peter Sinn, Christian Jackisch, Manfred Dietel, Toralf Reimer, Michael Untch, and Sibylle Loibl