ADP-dependent glucokinase as a novel onco-target for haematological malignancies

Warburg effect or aerobic glycolysis provides selective growth advantage to aggressive cancers. However, targeting oncogenic regulators of Warburg effect has always been challenging owing to the wide spectrum of roles of these molecules in multitude of cells. In this study, we present ADP-dependent...

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Bibliographic Details
Main Authors: Tandon, Amol (Author) , Birkenhagen, Jana (Author) , Nagalla, Deepthi (Author) , Kölker, Stefan (Author) , Sauer, Sven (Author)
Format: Article (Journal)
Language:English
Published: 12 August 2020
In: Scientific reports
Year: 2020, Volume: 10
ISSN:2045-2322
DOI:10.1038/s41598-020-70014-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41598-020-70014-0
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41598-020-70014-0
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Author Notes:Amol Tandon, Jana Birkenhagen, Deepthi Nagalla, Stefan Kölker & Sven Wolfgang Sauer