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A new sequential animal model for infection-related non-unions with segmental bone defect

The treatment of fracture-related infections (FRI) is still a challenge for orthopedic surgeons. The prevalence of FRI is particularly high in open fractures with extensive soft-tissue damage. This study aimed to develop a new two-step animal model for non-unions with segmental bone defects, which c...

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Main Authors: Helbig, Lars (Author) , Gühring, Thorsten (Author) , Titze, Nadine (Author) , Nurjadi, Dennis (Author) , Sonntag, Robert (Author) , Armbruster, Jonas (Author) , Wildemann, Britt (Author) , Schmidmaier, Gerhard (Author) , Grützner, Paul Alfred (Author) , Freischmidt, Holger (Author)
Format: Article (Journal)
Language:English
Published: 27 May 2020
In: BMC musculoskeletal disorders
Year: 2020, Volume: 21, Pages: 1-11
ISSN:1471-2474
DOI:10.1186/s12891-020-03355-6
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12891-020-03355-6
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Author Notes:Lars Helbig, Thorsten Guehring, Nadine Titze, Dennis Nurjadi, Robert Sonntag, Jonas Armbruster, Britt Wildemann, Gerhard Schmidmaier, Alfred Paul Gruetzner and Holger Freischmidt
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Summary:The treatment of fracture-related infections (FRI) is still a challenge for orthopedic surgeons. The prevalence of FRI is particularly high in open fractures with extensive soft-tissue damage. This study aimed to develop a new two-step animal model for non-unions with segmental bone defects, which could be used to evaluate new innovative bone substitutes to improve the therapeutic options in humans with FRI and bone defects.
Item Description:Gesehen am 14.10.2020
Physical Description:Online Resource
ISSN:1471-2474
DOI:10.1186/s12891-020-03355-6

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