A new sequential animal model for infection-related non-unions with segmental bone defect
The treatment of fracture-related infections (FRI) is still a challenge for orthopedic surgeons. The prevalence of FRI is particularly high in open fractures with extensive soft-tissue damage. This study aimed to develop a new two-step animal model for non-unions with segmental bone defects, which c...
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| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 May 2020
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| In: |
BMC musculoskeletal disorders
Year: 2020, Volume: 21, Pages: 1-11 |
| ISSN: | 1471-2474 |
| DOI: | 10.1186/s12891-020-03355-6 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12891-020-03355-6 |
| Author Notes: | Lars Helbig, Thorsten Guehring, Nadine Titze, Dennis Nurjadi, Robert Sonntag, Jonas Armbruster, Britt Wildemann, Gerhard Schmidmaier, Alfred Paul Gruetzner and Holger Freischmidt |
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| 520 | |a The treatment of fracture-related infections (FRI) is still a challenge for orthopedic surgeons. The prevalence of FRI is particularly high in open fractures with extensive soft-tissue damage. This study aimed to develop a new two-step animal model for non-unions with segmental bone defects, which could be used to evaluate new innovative bone substitutes to improve the therapeutic options in humans with FRI and bone defects. | ||
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