Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer

Pancreatic cancer consists of a heterogenous bulk of tumor cells and stroma cells which contribute to tumor progression by releasing angiogenic factors. Those factors can be detected as circulating serum factors. We performed a compartmentspecific analysis of tumor-derived and stroma-derived angioge...

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Main Authors: Kahlert, Christoph (Author) , Fiala, Maria (Author) , Musso, Gabriel (Author) , Halama, Niels (Author) , Keim, Sophia (Author) , Mazzone, Massimiliano (Author) , Lasitschka, Felix (Author) , Pecqueux, Mathieu (Author) , Klupp, Fee (Author) , Schmidt, Thomas (Author) , Rahbari, Nuh Nabi (Author) , Schölch, Sebastian (Author) , Pilarsky, Christian (Author) , Ulrich, Alexis (Author) , Schneider, Martin (Author) , Weitz, Jürgen (Author) , Koch, Moritz (Author)
Format: Article (Journal)
Language:English
Published: December 30, 2014
In: OncoTarget
Year: 2014, Volume: 5, Issue: 24, Pages: 12978-12989
ISSN:1949-2553
DOI:10.18632/oncotarget.2651
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.18632/oncotarget.2651
Verlag, lizenzpflichtig, Volltext: https://www.oncotarget.com/article/2651/text/
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Author Notes:Christoph Kahlert, Maria Fiala, Gabriel Musso, Niels Halama, Sophia Keim, Massimiliano Mazzone, Felix Lasitschka, Mathieu Pecqueux, Fee Klupp, Thomas Schmidt, Nuh Rahbari, Sebastian Schölch, Christian Pilarsky, Alexis Ulrich, Martin Schneider, Juergen Weitz, Moritz Koch
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Summary:Pancreatic cancer consists of a heterogenous bulk of tumor cells and stroma cells which contribute to tumor progression by releasing angiogenic factors. Those factors can be detected as circulating serum factors. We performed a compartmentspecific analysis of tumor-derived and stroma-derived angiogenic factors to identify biomarkers and molecular targets for the treatment of pancreatic cancer.
Item Description:Gesehen am 16.10.2020
Physical Description:Online Resource
ISSN:1949-2553
DOI:10.18632/oncotarget.2651