Clinical relevance of HLA antibody monitoring after kidney transplantation

In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a...

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Hauptverfasser: Morath, Christian (VerfasserIn) , Opelz, Gerhard (VerfasserIn) , Zeier, Martin (VerfasserIn) , Süsal, Caner (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 13 October 2014
In: Journal of immunology research

ISSN:2314-7156
DOI:10.1155/2014/845040
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://www.hindawi.com/journals/jir/2014/845040/
Verlag, lizenzpflichtig, Volltext: http://dx.doi.org/10.1155/2014/845040
Volltext
Verfasserangaben:Christian Morath, Gerhard Opelz, Martin Zeier, and Caner Süsal
Beschreibung
Zusammenfassung:In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a focus on risk factors for de novo alloantibody induction and recently published guidelines for monitoring of DSA during the posttransplant phase.
Beschreibung:Gesehen am 19.10.2020
Beschreibung:Online Resource
ISSN:2314-7156
DOI:10.1155/2014/845040