Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex®
Deregulated activation of mucosal lamina propria T cells plays a central role in the pathogenesis of intestinal inflammation. One of the means to attenuate T cell activation is by blocking the CD28/CD80 co-stimulatory pathway. Here we investigate RhuDex®, a small molecule that binds to human CD80, f...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
3 November 2014
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| In: |
Immunity, Inflammation and Disease
Year: 2014, Jahrgang: 2, Heft: 3, Pages: 166-180 |
| ISSN: | 2050-4527 |
| DOI: | 10.1002/iid3.34 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/iid3.34 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/iid3.34 
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| Verfasserangaben: | Anne-Kristin Heninger, Sabine Wentrup, Mohammed Al‐Saeedi, Serin Schiessling, Thomas Giese, Florian Wartha, Stefan Meuer, & Jutta Schröder‐Braunstein |
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