The relationship between posttraumatic growth and health-related quality of life in adult cancer survivors: a systematic review

Background - Studies have reported mixed findings on the relationship between posttraumatic growth (PTG) and health-related quality of life (HRQOL) in cancer survivors. This review aims to give an overview of these studies and to identify potential study- and sample-level factors that could contribu...

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Hauptverfasser: Liu, Zhunzhun (VerfasserIn) , Doege, Daniela (VerfasserIn) , Thong, Melissa S. Y. (VerfasserIn) , Arndt, Volker (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 18 July 2020
In: Journal of affective disorders
Year: 2020, Jahrgang: 276, Pages: 159-168
ISSN:1573-2517
DOI:10.1016/j.jad.2020.07.044
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jad.2020.07.044
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0165032720324897
Volltext
Verfasserangaben:Zhunzhun Liu, Daniela Doege, Melissa S.Y. Thong, Volker Arndt

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520 |a Background - Studies have reported mixed findings on the relationship between posttraumatic growth (PTG) and health-related quality of life (HRQOL) in cancer survivors. This review aims to give an overview of these studies and to identify potential study- and sample-level factors that could contribute to the heterogeneity of those findings on the relationship between PTG and HRQOL in cancer survivors. - Methods - Multiple electronic databases were systematically searched using the concepts ‘posttraumatic growth’, ‘cancer’, and ‘health-related quality of life’. Eligible studies (published until 2018) were reviewed, quality-assessed, and effect sizes were extracted and synthesized. - Results - Of the 37 included articles, 22 received a rating of ‘weak’, 11 ‘moderate’ and 4 ‘strong’ in study quality assessment. The overall sample comprised 7954 individuals, mean age of 55.30 years, >50% females, predominantly breast cancer, and survivors mainly within 5 years post-diagnosis. The synthesized results revealed a positive association between PTG and HRQOL (Fisher's z= 0.16) on a total scale, with significant high heterogeneity (I2=75%). Variations in HRQOL measurement and methodological inconsistency contributed to study-level differences of effect sizes. Sample-level characteristics such as geographic region, smaller sample sizes (n < 100) and so on contributed to heterogeneity. - Limitations - Studies assessing the relationship between PTG and HRQOL were heterogeneous, of weak study quality generally, and results were difficult to combine. - Conclusions - Most studies found a positive relationship between the factors suggesting that PTG may play a role for successful coping following cancer. However, studies of higher quality and longitudinal design are needed. 
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